Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States
© 2018 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Background: Recently, a newly developed cancer-specific multiattribute utility instrument based on the widely used health-related quality of life instrument, the European Organisation for Research and Treatment of Canc...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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Elsevier Inc.
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/68081 |
| _version_ | 1848761737811066880 |
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| author | Gamper, E. Holzner, B. King, M. Norman, Richard Viney, R. Nerich, V. Kemmler, G. |
| author_facet | Gamper, E. Holzner, B. King, M. Norman, Richard Viney, R. Nerich, V. Kemmler, G. |
| author_sort | Gamper, E. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2018 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Background: Recently, a newly developed cancer-specific multiattribute utility instrument based on the widely used health-related quality of life instrument, the European Organisation for Research and Treatment of Cancer QLQ-C30, was introduced: the QLU-C10D. For the elicitation of utility weights, a discrete choice experiment (DCE) was designed. Our aim was to investigate the DCE in terms of individual choice consistency and utility estimate consistency by applying a test-retest design. Methods: We conducted the study in general population samples in Germany and France. The DCE was administered via a web-based self-complete survey using online panels. Respondents were presented 16 choice sets comprising 11 attributes with 4 levels each. Retest was conducted 4 to 6 weeks after first assessment. We used kappa and percentage agreement as measures of choice consistency and both intraclass correlations and mean utility differences as measures of utility estimate consistency. Results: A total of 300 German respondents (31% female, mean age 48 years [SD 14]) and 305 French respondents (46% female, mean age 47 years [SD 16] ) completed test and retest assessments. Individual choice consistency was moderate to high (Germany: ? = 0.605, percentage agreement = 80.2%; France: ? = 0.411, percentage agreement = 70.6%). Utility estimate consistency was high when considering intraclass correlations (all > 0.79). Mean utility differences were 0.08 in the German sample and 0.05 in the French sample. Conclusions: Results indicate that the designed DCE elicits stable health state preferences rather than guesses or mood-specific or condition-specific judgments. Nevertheless, the identified mean utility differences between test and retest need to be taken into account when determining minimal important differences for the QLU-C10D in future research. |
| first_indexed | 2025-11-14T10:36:26Z |
| format | Journal Article |
| id | curtin-20.500.11937-68081 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:36:26Z |
| publishDate | 2018 |
| publisher | Elsevier Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-680812018-05-18T08:07:31Z Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States Gamper, E. Holzner, B. King, M. Norman, Richard Viney, R. Nerich, V. Kemmler, G. © 2018 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Background: Recently, a newly developed cancer-specific multiattribute utility instrument based on the widely used health-related quality of life instrument, the European Organisation for Research and Treatment of Cancer QLQ-C30, was introduced: the QLU-C10D. For the elicitation of utility weights, a discrete choice experiment (DCE) was designed. Our aim was to investigate the DCE in terms of individual choice consistency and utility estimate consistency by applying a test-retest design. Methods: We conducted the study in general population samples in Germany and France. The DCE was administered via a web-based self-complete survey using online panels. Respondents were presented 16 choice sets comprising 11 attributes with 4 levels each. Retest was conducted 4 to 6 weeks after first assessment. We used kappa and percentage agreement as measures of choice consistency and both intraclass correlations and mean utility differences as measures of utility estimate consistency. Results: A total of 300 German respondents (31% female, mean age 48 years [SD 14]) and 305 French respondents (46% female, mean age 47 years [SD 16] ) completed test and retest assessments. Individual choice consistency was moderate to high (Germany: ? = 0.605, percentage agreement = 80.2%; France: ? = 0.411, percentage agreement = 70.6%). Utility estimate consistency was high when considering intraclass correlations (all > 0.79). Mean utility differences were 0.08 in the German sample and 0.05 in the French sample. Conclusions: Results indicate that the designed DCE elicits stable health state preferences rather than guesses or mood-specific or condition-specific judgments. Nevertheless, the identified mean utility differences between test and retest need to be taken into account when determining minimal important differences for the QLU-C10D in future research. 2018 Journal Article http://hdl.handle.net/20.500.11937/68081 10.1016/j.jval.2017.11.012 Elsevier Inc. restricted |
| spellingShingle | Gamper, E. Holzner, B. King, M. Norman, Richard Viney, R. Nerich, V. Kemmler, G. Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States |
| title | Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States |
| title_full | Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States |
| title_fullStr | Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States |
| title_full_unstemmed | Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States |
| title_short | Test-Retest Reliability of Discrete Choice Experiment for Valuations of QLU-C10D Health States |
| title_sort | test-retest reliability of discrete choice experiment for valuations of qlu-c10d health states |
| url | http://hdl.handle.net/20.500.11937/68081 |