Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey
© 2018, The Author(s) 2018. Background: The aim of this study was to investigate the proportion of patients who have suboptimal adherence to oral anticoagulant (OAC), identify the predictors of adherence, and determine whether patient-related factors vary across adherence levels in Australia. Method...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/67242 |
| _version_ | 1848761514553507840 |
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| author | Obamiro, K. Chalmers, Leanne Lee, K. Bereznicki, B. Bereznicki, L. |
| author_facet | Obamiro, K. Chalmers, Leanne Lee, K. Bereznicki, B. Bereznicki, L. |
| author_sort | Obamiro, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2018, The Author(s) 2018. Background: The aim of this study was to investigate the proportion of patients who have suboptimal adherence to oral anticoagulant (OAC), identify the predictors of adherence, and determine whether patient-related factors vary across adherence levels in Australia. Methods: Respondents were recruited for an online survey using Facebook. Survey instruments included the Morisky Medication Adherence Scale, the Anticoagulation Knowledge Tool, the Perception of Anticoagulant Treatment Questionnaires, and a modified Cancer Information Overload scale. Predictors of medication adherence were identified using ordinal regression analysis. Results: Of the 386 responses eligible for analysis, only 54.9% reported a high level of adherence. Participants aged 65 years or younger were less likely to have high adherence compared to older participants (odds ratio [OR], 0.54; 95% confidence interval [CI] , 0.33-0.88; P =.013), while females were more likely to be highly adherent compared to males (OR, 1.69; 95% CI, 1.08-2.64; P =.023). The analyses showed that age, gender, treatment satisfaction, information overload, concerns about making mistake when taking OACs, and cost of medication were significant predictors of adherence. Conclusion: Self-reported suboptimal adherence to OAC is common among patients with atrial fibrillation. A focus on supporting people who are at higher risk of suboptimal adherence is needed to maximize the benefit of OAC therapy in this population. |
| first_indexed | 2025-11-14T10:32:53Z |
| format | Journal Article |
| id | curtin-20.500.11937-67242 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:32:53Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-672422020-06-15T04:37:04Z Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey Obamiro, K. Chalmers, Leanne Lee, K. Bereznicki, B. Bereznicki, L. © 2018, The Author(s) 2018. Background: The aim of this study was to investigate the proportion of patients who have suboptimal adherence to oral anticoagulant (OAC), identify the predictors of adherence, and determine whether patient-related factors vary across adherence levels in Australia. Methods: Respondents were recruited for an online survey using Facebook. Survey instruments included the Morisky Medication Adherence Scale, the Anticoagulation Knowledge Tool, the Perception of Anticoagulant Treatment Questionnaires, and a modified Cancer Information Overload scale. Predictors of medication adherence were identified using ordinal regression analysis. Results: Of the 386 responses eligible for analysis, only 54.9% reported a high level of adherence. Participants aged 65 years or younger were less likely to have high adherence compared to older participants (odds ratio [OR], 0.54; 95% confidence interval [CI] , 0.33-0.88; P =.013), while females were more likely to be highly adherent compared to males (OR, 1.69; 95% CI, 1.08-2.64; P =.023). The analyses showed that age, gender, treatment satisfaction, information overload, concerns about making mistake when taking OACs, and cost of medication were significant predictors of adherence. Conclusion: Self-reported suboptimal adherence to OAC is common among patients with atrial fibrillation. A focus on supporting people who are at higher risk of suboptimal adherence is needed to maximize the benefit of OAC therapy in this population. 2018 Journal Article http://hdl.handle.net/20.500.11937/67242 10.1177/1074248418770201 restricted |
| spellingShingle | Obamiro, K. Chalmers, Leanne Lee, K. Bereznicki, B. Bereznicki, L. Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey |
| title | Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey |
| title_full | Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey |
| title_fullStr | Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey |
| title_full_unstemmed | Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey |
| title_short | Adherence to Oral Anticoagulants in Atrial Fibrillation: An Australian Survey |
| title_sort | adherence to oral anticoagulants in atrial fibrillation: an australian survey |
| url | http://hdl.handle.net/20.500.11937/67242 |