Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis
Endovascular stent graft repair has become a common treatment for complicated Stanford type B aortic dissection to restore true lumen flow and induce false lumen thrombosis. Using computational fluid dynamics, this study reports the differences in flow patterns and wall shear stress distribution in...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
John Wiley & Sons Ltd.
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/67168 |
| _version_ | 1848761493902852096 |
|---|---|
| author | Wan Ab Naim, W. Ganesan, P. Sun, Zhonghua Lei, J. Jansen, S. Hashim, S. Ho, T. Lim, E. |
| author_facet | Wan Ab Naim, W. Ganesan, P. Sun, Zhonghua Lei, J. Jansen, S. Hashim, S. Ho, T. Lim, E. |
| author_sort | Wan Ab Naim, W. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Endovascular stent graft repair has become a common treatment for complicated Stanford type B aortic dissection to restore true lumen flow and induce false lumen thrombosis. Using computational fluid dynamics, this study reports the differences in flow patterns and wall shear stress distribution in complicated Stanford type B aortic dissection patients after endovascular stent graft repair. Five patients were included in this study: 2 have more than 80% false lumen thrombosis (group 1), while 3 others had less than 80% false lumen thrombosis (group 2) within 1 year following endovascular repair. Group 1 patients had concentrated re-entry tears around the abdominal branches only, while group 2 patients had re-entry tears that spread along the dissection line. Blood flow inside the false lumen which affected thrombus formation increased with the number of re-entry tears and when only small amounts of blood that entered the false lumen exited through the branches. In those cases where dissection extended below the abdominal branches (group 2), patients with fewer re-entry tears and longer distance between the tears had low wall shear stress contributing to thrombosis. This work provides an insight into predicting the development of complete or incomplete false lumen thrombosis and has implications for patient selection for treatment. |
| first_indexed | 2025-11-14T10:32:33Z |
| format | Journal Article |
| id | curtin-20.500.11937-67168 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:32:33Z |
| publishDate | 2018 |
| publisher | John Wiley & Sons Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-671682018-08-21T02:01:37Z Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis Wan Ab Naim, W. Ganesan, P. Sun, Zhonghua Lei, J. Jansen, S. Hashim, S. Ho, T. Lim, E. Endovascular stent graft repair has become a common treatment for complicated Stanford type B aortic dissection to restore true lumen flow and induce false lumen thrombosis. Using computational fluid dynamics, this study reports the differences in flow patterns and wall shear stress distribution in complicated Stanford type B aortic dissection patients after endovascular stent graft repair. Five patients were included in this study: 2 have more than 80% false lumen thrombosis (group 1), while 3 others had less than 80% false lumen thrombosis (group 2) within 1 year following endovascular repair. Group 1 patients had concentrated re-entry tears around the abdominal branches only, while group 2 patients had re-entry tears that spread along the dissection line. Blood flow inside the false lumen which affected thrombus formation increased with the number of re-entry tears and when only small amounts of blood that entered the false lumen exited through the branches. In those cases where dissection extended below the abdominal branches (group 2), patients with fewer re-entry tears and longer distance between the tears had low wall shear stress contributing to thrombosis. This work provides an insight into predicting the development of complete or incomplete false lumen thrombosis and has implications for patient selection for treatment. 2018 Journal Article http://hdl.handle.net/20.500.11937/67168 10.1002/cnm.2961 John Wiley & Sons Ltd. restricted |
| spellingShingle | Wan Ab Naim, W. Ganesan, P. Sun, Zhonghua Lei, J. Jansen, S. Hashim, S. Ho, T. Lim, E. Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis |
| title | Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis |
| title_full | Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis |
| title_fullStr | Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis |
| title_full_unstemmed | Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis |
| title_short | Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis |
| title_sort | flow pattern analysis in type b aortic dissection patients after stent-grafting repair: comparison between complete and incomplete false lumen thrombosis |
| url | http://hdl.handle.net/20.500.11937/67168 |