Elderly dendritic cells respond to LPS/IFN-Î³ and CD40L stimulation despite incomplete maturation

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Elderly dendritic cells respond to LPS/IFN-Î³ and CD40L stimulation despite incomplete maturation

There is evidence that dendritic cells (DCs) undergo age-related changes that modulate their function with their key role being priming antigen-specific effector T cells. This occurs once DCs develop into antigen-presenting cells in response to stimuli/danger signals. However, the effects of aging o...

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Bibliographic Details
Main Authors:	Gardner, J., Cornwall, S., Musk, A., Alvarez, J., Mamotte, Cyril, Jackaman, Connie, Nowak, A., Nelson, Delia
Format:	Journal Article
Published:	Public Library of Science 2018
Online Access:	http://hdl.handle.net/20.500.11937/66811

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