Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis

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Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis

© 2018 American Chemical Society. Inhibition of the mycolic acid pathway has proven a viable strategy in antitubercular drug discovery. The AccA3/AccD4/FadD32/Pks13 complex of Mycobacterium tuberculosis constitutes an essential biosynthetic mechanism for mycolic acids. Small molecules targeting the...

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Bibliographic Details
Main Authors:	Zhang, W., Lun, S., Wang, S., Jiang, X., Yang, F., Tang, J., Manson, A., Earl, A., Gunosewoyo, Hendra, Bishai, W., Yu, L.
Format:	Journal Article
Published:	American Chemical Society 2018
Online Access:	http://purl.org/au-research/grants/arc/DE160100482 http://hdl.handle.net/20.500.11937/66509

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