Genomic analyses identify molecular subtypes of pancreatic cancer

Genomic analyses identify molecular subtypes of pancreatic cancer

© 2016 Macmillan Publishers Limited. All rights reserved.Integrated genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/SLIT signalling, G1/S transition, SWI-SNF, chromatin modification, DN...

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Main Authors: Bailey, P., Chang, D., Nones, K., Johns, A., Patch, A., Gingras, M., Miller, D., Christ, A., Bruxner, T., Quinn, M., Nourse, C., Murtaugh, L., Harliwong, I., Idrisoglu, S., Manning, S., Nourbakhsh, E., Wani, S., Fink, L., Holmes, O., Chin, V., Anderson, M., Kazakoff, S., Leonard, C., Newell, F., Waddell, N., Wood, S., Xu, Q., Wilson, P., Cloonan, N., Kassahn, K., Taylor, D., Quek, K., Robertson, A., Pantano, L., Mincarelli, L., Sanchez, L., Evers, L., Wu, J., Pinese, M., Cowley, M., Jones, M., Colvin, E., Nagrial, A., Humphrey, E., Chantrill, L., Mawson, A., Humphris, J., Chou, A., Pajic, M., Scarlett, C., Pinho, A., Giry-Laterriere, M., Rooman, I., Samra, J., Kench, J., Lovell, J., Merrett, N., Toon, C., Epari, K., Nguyen, N., Barbour, A., Zeps, Nikolajs, Moran-Jones, K., Jamieson, N., Graham, J., Duthie, F., Oien, K., Hair, J., Gruetzmann, R., Maitra, A., Iacobuzio-Donahue, C., Wolfgang, C., Morgan, R., Lawlor, R., Corbo, V., Bassi, C., Rusev, B., Capelli, P., Salvia, R., Tortora, G., Mukhopadhyay, D., Petersen, G., Munzy, D., Fisher, W., Karim, S., Eshleman, J., Hruban, R., Pilarsky, C., Morton, J., Sansom, O., Scarpa, A., Musgrove, E., Bailey, U., Hofmann, O., Sutherland, R., Wheeler, D., Gill, A., Gibbs, R., Pearson, J., Biankin, A., Grimmond, S.
Format: Journal Article
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/20.500.11937/66359

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