Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles
A series of tetrazoles-containing molecules were investigated for their impact on calcium oxalate monohydrate (COM) crystallisation for the first time. COM is the main constituent of kidney stones, a common pathological mineral in humans. The tetrazole series was found to inhibit the morphology, cry...
| Main Author: | |
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| Format: | Thesis |
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Curtin University
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/65993 |
| _version_ | 1848760566449963008 |
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| author | McMulkin, Calum |
| author_facet | McMulkin, Calum |
| author_sort | McMulkin, Calum |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | A series of tetrazoles-containing molecules were investigated for their impact on calcium oxalate monohydrate (COM) crystallisation for the first time. COM is the main constituent of kidney stones, a common pathological mineral in humans. The tetrazole series was found to inhibit the morphology, crystal growth and nucleation of COM directly through selective adsorption or by a complexation mechanism, to varying degrees. Structural trends and which of the tetrazole molecules as crystal growth modifiers were confirmed. |
| first_indexed | 2025-11-14T10:17:49Z |
| format | Thesis |
| id | curtin-20.500.11937-65993 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:17:49Z |
| publishDate | 2017 |
| publisher | Curtin University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-659932018-03-08T00:15:10Z Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles McMulkin, Calum A series of tetrazoles-containing molecules were investigated for their impact on calcium oxalate monohydrate (COM) crystallisation for the first time. COM is the main constituent of kidney stones, a common pathological mineral in humans. The tetrazole series was found to inhibit the morphology, crystal growth and nucleation of COM directly through selective adsorption or by a complexation mechanism, to varying degrees. Structural trends and which of the tetrazole molecules as crystal growth modifiers were confirmed. 2017 Thesis http://hdl.handle.net/20.500.11937/65993 Curtin University fulltext |
| spellingShingle | McMulkin, Calum Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles |
| title | Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles |
| title_full | Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles |
| title_fullStr | Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles |
| title_full_unstemmed | Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles |
| title_short | Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles |
| title_sort | crystallisation of calcium oxalate solids in the presence of tetrazoles |
| url | http://hdl.handle.net/20.500.11937/65993 |