Crystallisation of Calcium Oxalate Solids in the Presence of Tetrazoles
A series of tetrazoles-containing molecules were investigated for their impact on calcium oxalate monohydrate (COM) crystallisation for the first time. COM is the main constituent of kidney stones, a common pathological mineral in humans. The tetrazole series was found to inhibit the morphology, cry...
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| Format: | Thesis |
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Curtin University
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/65993 |
| Summary: | A series of tetrazoles-containing molecules were investigated for their impact on calcium oxalate monohydrate (COM) crystallisation for the first time. COM is the main constituent of kidney stones, a common pathological mineral in humans. The tetrazole series was found to inhibit the morphology, crystal growth and nucleation of COM directly through selective adsorption or by a complexation mechanism, to varying degrees. Structural trends and which of the tetrazole molecules as crystal growth modifiers were confirmed. |
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