Distribution and diversity of bacterial secretion systems across metagenomic datasets
Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from type I through type VI secretion system (T1SS–T...
| Main Authors: | , , |
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| Format: | Journal Article |
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Wiley-Blackwell Publishing Ltd.
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/6413 |
| _version_ | 1848745069371195392 |
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| author | Barret, M. Egan, F. O'Gara, Fergal |
| author_facet | Barret, M. Egan, F. O'Gara, Fergal |
| author_sort | Barret, M. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from type I through type VI secretion system (T1SS–T6SS). In this study the prevalence of these secretion systems in 312 publicly available microbiomes derived from a wide range of ecosystems was investigated by a gene-centric approach. Our analysis demonstrates that some secretion systems are over-represented in some specific samples. In addition, some T3SS and T6SS phylogenetic clusters were specifically enriched in particular ecological niches, which could indicate specific bacterial adaptation to these environments. |
| first_indexed | 2025-11-14T06:11:30Z |
| format | Journal Article |
| id | curtin-20.500.11937-6413 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:11:30Z |
| publishDate | 2013 |
| publisher | Wiley-Blackwell Publishing Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-64132017-09-13T14:42:16Z Distribution and diversity of bacterial secretion systems across metagenomic datasets Barret, M. Egan, F. O'Gara, Fergal Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from type I through type VI secretion system (T1SS–T6SS). In this study the prevalence of these secretion systems in 312 publicly available microbiomes derived from a wide range of ecosystems was investigated by a gene-centric approach. Our analysis demonstrates that some secretion systems are over-represented in some specific samples. In addition, some T3SS and T6SS phylogenetic clusters were specifically enriched in particular ecological niches, which could indicate specific bacterial adaptation to these environments. 2013 Journal Article http://hdl.handle.net/20.500.11937/6413 10.1111/j.1758-2229.2012.00394.x Wiley-Blackwell Publishing Ltd. restricted |
| spellingShingle | Barret, M. Egan, F. O'Gara, Fergal Distribution and diversity of bacterial secretion systems across metagenomic datasets |
| title | Distribution and diversity of bacterial secretion systems across metagenomic datasets |
| title_full | Distribution and diversity of bacterial secretion systems across metagenomic datasets |
| title_fullStr | Distribution and diversity of bacterial secretion systems across metagenomic datasets |
| title_full_unstemmed | Distribution and diversity of bacterial secretion systems across metagenomic datasets |
| title_short | Distribution and diversity of bacterial secretion systems across metagenomic datasets |
| title_sort | distribution and diversity of bacterial secretion systems across metagenomic datasets |
| url | http://hdl.handle.net/20.500.11937/6413 |