Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient

Background and Objectives: Three-dimensional (3D) printing has been increasingly used in medicine with applications in the diagnostic assessment of disease extent, medical education and training, preoperative planning, and surgical simulation. The use of 3D printing in brain tumors is very limited....

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Main Authors: Lau, Ivan, Squelch, Andrew, Wan, Y., Wong, A., Ducke, W., Sun, Zhonghua
Format: Journal Article
Published: Springer Media Publishing 2017
Online Access:http://hdl.handle.net/20.500.11937/63521
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author Lau, Ivan
Squelch, Andrew
Wan, Y.
Wong, A.
Ducke, W.
Sun, Zhonghua
author_facet Lau, Ivan
Squelch, Andrew
Wan, Y.
Wong, A.
Ducke, W.
Sun, Zhonghua
author_sort Lau, Ivan
building Curtin Institutional Repository
collection Online Access
description Background and Objectives: Three-dimensional (3D) printing has been increasingly used in medicine with applications in the diagnostic assessment of disease extent, medical education and training, preoperative planning, and surgical simulation. The use of 3D printing in brain tumors is very limited. In this study, we presented our preliminary experience of creating patient-specific 3D printed model of a brain tumor in a pediatric patient and demonstrated the feasibility of using 3D printing in delineating brain anatomy and tumor. Materials and Methods: A life-size 3D printed brain model of a 6-year-old girl, who was diagnosed with pilocytic astrocytoma, was generated. The model was created using high-resolution magnetic resonance images which were postprocessed and segmented to demonstrate normal anatomical structures and the tumor. The tumor was confirmed to be Grade I pilocytic astrocytoma after neurosurgery. Results: 3D printed model was found to provide realistic visualization of brain anatomical structures and tumor, and enhance understanding of pathology in relation to the surrounding structures. The mean difference in diameter measurements of the brain tumor was 0.53 mm (0.98%) between the 3D printed model and computerized model. Conclusions: This study shows it is feasible to generate a 3D printed model of brain tumor with encouraging results achieved to replicate brain anatomy and tumor. 3D printed model of brain tumor could serve as an excellent tool for preoperative planning and simulation of surgical procedures, which deserve to be investigated in further studies.
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spelling curtin-20.500.11937-635212018-04-27T03:30:47Z Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient Lau, Ivan Squelch, Andrew Wan, Y. Wong, A. Ducke, W. Sun, Zhonghua Background and Objectives: Three-dimensional (3D) printing has been increasingly used in medicine with applications in the diagnostic assessment of disease extent, medical education and training, preoperative planning, and surgical simulation. The use of 3D printing in brain tumors is very limited. In this study, we presented our preliminary experience of creating patient-specific 3D printed model of a brain tumor in a pediatric patient and demonstrated the feasibility of using 3D printing in delineating brain anatomy and tumor. Materials and Methods: A life-size 3D printed brain model of a 6-year-old girl, who was diagnosed with pilocytic astrocytoma, was generated. The model was created using high-resolution magnetic resonance images which were postprocessed and segmented to demonstrate normal anatomical structures and the tumor. The tumor was confirmed to be Grade I pilocytic astrocytoma after neurosurgery. Results: 3D printed model was found to provide realistic visualization of brain anatomical structures and tumor, and enhance understanding of pathology in relation to the surrounding structures. The mean difference in diameter measurements of the brain tumor was 0.53 mm (0.98%) between the 3D printed model and computerized model. Conclusions: This study shows it is feasible to generate a 3D printed model of brain tumor with encouraging results achieved to replicate brain anatomy and tumor. 3D printed model of brain tumor could serve as an excellent tool for preoperative planning and simulation of surgical procedures, which deserve to be investigated in further studies. 2017 Journal Article http://hdl.handle.net/20.500.11937/63521 10.4103/digm.digm_25_17 Springer Media Publishing unknown
spellingShingle Lau, Ivan
Squelch, Andrew
Wan, Y.
Wong, A.
Ducke, W.
Sun, Zhonghua
Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient
title Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient
title_full Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient
title_fullStr Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient
title_full_unstemmed Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient
title_short Patient-specific 3D printed model in delineating brain glioma and surrounding structures in a pediatric patient
title_sort patient-specific 3d printed model in delineating brain glioma and surrounding structures in a pediatric patient
url http://hdl.handle.net/20.500.11937/63521