Simultaneous determination of pentoxifylline, metabolites M1 (lisofylline), M4 and M5, and caffeine in plasma and dried blood spots for pharmacokinetic studies in preterm infants and neonates

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Simultaneous determination of pentoxifylline, metabolites M1 (lisofylline), M4 and M5, and caffeine in plasma and dried blood spots for pharmacokinetic studies in preterm infants and neonates

© 2017 Elsevier B.V. Advances in bioanalytical methods are facilitating micro-volume and dried blood spot (DBS) analysis of drugs in biological matrices for pharmacokinetic studies in children and neonates. We sought to develop a UPLC–MS/MS assay for simultaneous measurement of caffeine, pentoxifyll...

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Bibliographic Details
Main Authors:	Page-Sharp, Madhu, Strunk, T., Salman, S., Hibbert, J., Patole, S., Manning, L., Batty, Kevin
Format:	Journal Article
Published:	Elsevier Science BV 2017
Online Access:	http://hdl.handle.net/20.500.11937/63456

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