Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs
© 2017, Springer Science+Business Media New York. Autism spectrum disorder (ASD) has been associated with gastrointestinal (GI) problems, but the nature of this association is unclear. Parents to siblings, concordant or discordant for ASD (N = 217), participated in a web survey covering mother’s...
| Main Authors: | , , , , |
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| Format: | Journal Article |
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Springer New York LLC
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/63200 |
| _version_ | 1848761021307551744 |
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| author | Isaksson, J. Pettersson, E. Kostrzewa, E. Diaz Heijtz, R. Bolte, Sven |
| author_facet | Isaksson, J. Pettersson, E. Kostrzewa, E. Diaz Heijtz, R. Bolte, Sven |
| author_sort | Isaksson, J. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2017, Springer Science+Business Media New York. Autism spectrum disorder (ASD) has been associated with gastrointestinal (GI) problems, but the nature of this association is unclear. Parents to siblings, concordant or discordant for ASD (N = 217), participated in a web survey covering mother’s weight gain during pregnancy, maternal viral/bacterial infection and use of antibiotics, duration of breastfeeding, mode of delivery, birth weight and child GI problems. ASD was associated with GI problems and perinatal environmental risk, based on a summation of maternal infection and antibiotic use during pregnancy and/or the breastfeeding period. The association between GI problems and ASD remained within the sibling pairs (β = 1.23; p < .001) in the adjusted model. Our results indicate non-shared environmental effects on the ASD/GI association, but none of the factors examined explained the link. |
| first_indexed | 2025-11-14T10:25:03Z |
| format | Journal Article |
| id | curtin-20.500.11937-63200 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:25:03Z |
| publishDate | 2017 |
| publisher | Springer New York LLC |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-632002018-02-06T06:23:52Z Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs Isaksson, J. Pettersson, E. Kostrzewa, E. Diaz Heijtz, R. Bolte, Sven © 2017, Springer Science+Business Media New York. Autism spectrum disorder (ASD) has been associated with gastrointestinal (GI) problems, but the nature of this association is unclear. Parents to siblings, concordant or discordant for ASD (N = 217), participated in a web survey covering mother’s weight gain during pregnancy, maternal viral/bacterial infection and use of antibiotics, duration of breastfeeding, mode of delivery, birth weight and child GI problems. ASD was associated with GI problems and perinatal environmental risk, based on a summation of maternal infection and antibiotic use during pregnancy and/or the breastfeeding period. The association between GI problems and ASD remained within the sibling pairs (β = 1.23; p < .001) in the adjusted model. Our results indicate non-shared environmental effects on the ASD/GI association, but none of the factors examined explained the link. 2017 Journal Article http://hdl.handle.net/20.500.11937/63200 10.1007/s10803-017-3169-2 Springer New York LLC restricted |
| spellingShingle | Isaksson, J. Pettersson, E. Kostrzewa, E. Diaz Heijtz, R. Bolte, Sven Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs |
| title | Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs |
| title_full | Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs |
| title_fullStr | Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs |
| title_full_unstemmed | Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs |
| title_short | Brief Report: Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs |
| title_sort | brief report: association between autism spectrum disorder, gastrointestinal problems and perinatal risk factors within sibling pairs |
| url | http://hdl.handle.net/20.500.11937/63200 |