Bronchial brushings for investigating airway inflammation and remodelling

Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable, severe in large number and refractory to treatment in many. However, there have been no new significant treatments despite intense research and bi...

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Main Authors: Looi, K., Sutanto, E., Banerjee, B., Garratt, L., Ling, K., Foo, C., Stick, S., Kicic, Anthony
Format: Journal Article
Published: Wiley-Blackwell Publishing Asia 2011
Online Access:http://hdl.handle.net/20.500.11937/63146
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author Looi, K.
Sutanto, E.
Banerjee, B.
Garratt, L.
Ling, K.
Foo, C.
Stick, S.
Kicic, Anthony
author_facet Looi, K.
Sutanto, E.
Banerjee, B.
Garratt, L.
Ling, K.
Foo, C.
Stick, S.
Kicic, Anthony
author_sort Looi, K.
building Curtin Institutional Repository
collection Online Access
description Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable, severe in large number and refractory to treatment in many. However, there have been no new significant treatments despite intense research and billions of dollars. The advancement in our understanding in this disease has been limited due to its heterogeneity, genetic complexity and has severely been hampered particularly in children by the difficulty in obtaining relevant target organ tissue. This review attempts to provide an overview of the currently used and recently developed/adapted techniques used to obtain lung tissue with specific reference to the airway epithelium. © 2011 The Authors Respirology © 2011 Asian Pacific Society of Respirology.
first_indexed 2025-11-14T10:24:49Z
format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:24:49Z
publishDate 2011
publisher Wiley-Blackwell Publishing Asia
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-631462018-02-06T06:23:09Z Bronchial brushings for investigating airway inflammation and remodelling Looi, K. Sutanto, E. Banerjee, B. Garratt, L. Ling, K. Foo, C. Stick, S. Kicic, Anthony Asthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable, severe in large number and refractory to treatment in many. However, there have been no new significant treatments despite intense research and billions of dollars. The advancement in our understanding in this disease has been limited due to its heterogeneity, genetic complexity and has severely been hampered particularly in children by the difficulty in obtaining relevant target organ tissue. This review attempts to provide an overview of the currently used and recently developed/adapted techniques used to obtain lung tissue with specific reference to the airway epithelium. © 2011 The Authors Respirology © 2011 Asian Pacific Society of Respirology. 2011 Journal Article http://hdl.handle.net/20.500.11937/63146 10.1111/j.1440-1843.2011.02001.x Wiley-Blackwell Publishing Asia unknown
spellingShingle Looi, K.
Sutanto, E.
Banerjee, B.
Garratt, L.
Ling, K.
Foo, C.
Stick, S.
Kicic, Anthony
Bronchial brushings for investigating airway inflammation and remodelling
title Bronchial brushings for investigating airway inflammation and remodelling
title_full Bronchial brushings for investigating airway inflammation and remodelling
title_fullStr Bronchial brushings for investigating airway inflammation and remodelling
title_full_unstemmed Bronchial brushings for investigating airway inflammation and remodelling
title_short Bronchial brushings for investigating airway inflammation and remodelling
title_sort bronchial brushings for investigating airway inflammation and remodelling
url http://hdl.handle.net/20.500.11937/63146