Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam
The incidence of prostate cancer has increased in Vietnam, but there have been few studies of the risk factors associated with this change. This retrospective case-control study investigated the relation of the intake of carotenoids and their food sources to prostate cancer risk. A sample of 652 par...
| Main Authors: | , , , , |
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| Format: | Journal Article |
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MDPI Publishing
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/62209 |
| _version_ | 1848760808793702400 |
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| author | Van Hoang, D. Pham, N. Lee, Andy Tran, D. Binns, Colin |
| author_facet | Van Hoang, D. Pham, N. Lee, Andy Tran, D. Binns, Colin |
| author_sort | Van Hoang, D. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The incidence of prostate cancer has increased in Vietnam, but there have been few studies of the risk factors associated with this change. This retrospective case-control study investigated the relation of the intake of carotenoids and their food sources to prostate cancer risk. A sample of 652 participants (244 incident prostate cancer patients, aged 64-75 years, and 408 age frequency-matched controls) were recruited in Ho Chi Minh City during 2013-2015. The habitual diet was ascertained with a validated food-frequency questionnaire, and other factors including demographic and lifestyle characteristics were assessed via face-to-face interviews by trained nurses. Multivariate-adjusted odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regression models. The risk of prostate cancer decreased with increasing intakes of lycopene, tomatoes, and carrots; the respective ORs (95% CIs) were 0.46 (0.27, 0.77), 0.39 (0.23, 0.66), and 0.35 (0.21, 0.58), when comparing the highest with the lowest tertile of intake (p for trend < 0.01). No statistically significant associations were found for the intake of a-carotene, ß-carotene, ß-cryptoxanthin, lutein, zeaxanthin, and major food sources of carotenoids. In conclusion, Vietnamese men with a higher intake of lycopene, tomatoes, and carrots may have a lower risk of prostate cancer. However, large prospective studies are needed in this population to confirm this finding. |
| first_indexed | 2025-11-14T10:21:40Z |
| format | Journal Article |
| id | curtin-20.500.11937-62209 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:21:40Z |
| publishDate | 2018 |
| publisher | MDPI Publishing |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-622092021-01-13T03:09:37Z Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam Van Hoang, D. Pham, N. Lee, Andy Tran, D. Binns, Colin The incidence of prostate cancer has increased in Vietnam, but there have been few studies of the risk factors associated with this change. This retrospective case-control study investigated the relation of the intake of carotenoids and their food sources to prostate cancer risk. A sample of 652 participants (244 incident prostate cancer patients, aged 64-75 years, and 408 age frequency-matched controls) were recruited in Ho Chi Minh City during 2013-2015. The habitual diet was ascertained with a validated food-frequency questionnaire, and other factors including demographic and lifestyle characteristics were assessed via face-to-face interviews by trained nurses. Multivariate-adjusted odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regression models. The risk of prostate cancer decreased with increasing intakes of lycopene, tomatoes, and carrots; the respective ORs (95% CIs) were 0.46 (0.27, 0.77), 0.39 (0.23, 0.66), and 0.35 (0.21, 0.58), when comparing the highest with the lowest tertile of intake (p for trend < 0.01). No statistically significant associations were found for the intake of a-carotene, ß-carotene, ß-cryptoxanthin, lutein, zeaxanthin, and major food sources of carotenoids. In conclusion, Vietnamese men with a higher intake of lycopene, tomatoes, and carrots may have a lower risk of prostate cancer. However, large prospective studies are needed in this population to confirm this finding. 2018 Journal Article http://hdl.handle.net/20.500.11937/62209 10.3390/nu10010070 http://creativecommons.org/licenses/by/4.0/ MDPI Publishing fulltext |
| spellingShingle | Van Hoang, D. Pham, N. Lee, Andy Tran, D. Binns, Colin Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam |
| title | Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam |
| title_full | Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam |
| title_fullStr | Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam |
| title_full_unstemmed | Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam |
| title_short | Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam |
| title_sort | dietary carotenoid intakes and prostate cancer risk: a case-control study from vietnam |
| url | http://hdl.handle.net/20.500.11937/62209 |