Triple negative breast cancer in Asia: An insider's view
While tremendous improvement has been made for the treatment of breast cancers, the treatment of triple negative breast cancer (TNBC) still remains a challenge due to its aggressive characteristics and limited treatment options. Most of the studies on TNBC were conducted in Western population and TN...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
W B Saunders co Ltd
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/61036 |
| _version_ | 1848760655228698624 |
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| author | Wang, C. Kar, S. Lai, X. Cai, W. Arfuso, Frank Sethi, G. Lobie, P. Goh, B. Lim, L. Hartman, M. Chan, C. Lee, S. Tan, S. Kumar, A. |
| author_facet | Wang, C. Kar, S. Lai, X. Cai, W. Arfuso, Frank Sethi, G. Lobie, P. Goh, B. Lim, L. Hartman, M. Chan, C. Lee, S. Tan, S. Kumar, A. |
| author_sort | Wang, C. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | While tremendous improvement has been made for the treatment of breast cancers, the treatment of triple negative breast cancer (TNBC) still remains a challenge due to its aggressive characteristics and limited treatment options. Most of the studies on TNBC were conducted in Western population and TNBC is reported to be more frequent in the African women. This review encapsulates the studies conducted on TNBC patients in Asian population and elucidates the similarities and differences between these two regions. The current treatment of TNBC includes surgery, radiotherapy and chemotherapy. In addition to the current chemotherapies, which mainly include cytotoxic agents, such as taxanes and anthracyclines, many clinical trials are investigating the potential use of other chemotherapy drugs, targeted therapeutics and combinational therapies to treat TNBC. Moreover, this review also integrates the studies involving novel markers, which will help us to dissect the pathologic process of TNBC and in turn facilitate the development of better treatment strategies to combat TNBC. |
| first_indexed | 2025-11-14T10:19:14Z |
| format | Journal Article |
| id | curtin-20.500.11937-61036 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:19:14Z |
| publishDate | 2018 |
| publisher | W B Saunders co Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-610362018-04-17T07:25:21Z Triple negative breast cancer in Asia: An insider's view Wang, C. Kar, S. Lai, X. Cai, W. Arfuso, Frank Sethi, G. Lobie, P. Goh, B. Lim, L. Hartman, M. Chan, C. Lee, S. Tan, S. Kumar, A. While tremendous improvement has been made for the treatment of breast cancers, the treatment of triple negative breast cancer (TNBC) still remains a challenge due to its aggressive characteristics and limited treatment options. Most of the studies on TNBC were conducted in Western population and TNBC is reported to be more frequent in the African women. This review encapsulates the studies conducted on TNBC patients in Asian population and elucidates the similarities and differences between these two regions. The current treatment of TNBC includes surgery, radiotherapy and chemotherapy. In addition to the current chemotherapies, which mainly include cytotoxic agents, such as taxanes and anthracyclines, many clinical trials are investigating the potential use of other chemotherapy drugs, targeted therapeutics and combinational therapies to treat TNBC. Moreover, this review also integrates the studies involving novel markers, which will help us to dissect the pathologic process of TNBC and in turn facilitate the development of better treatment strategies to combat TNBC. 2018 Journal Article http://hdl.handle.net/20.500.11937/61036 10.1016/j.ctrv.2017.10.014 W B Saunders co Ltd restricted |
| spellingShingle | Wang, C. Kar, S. Lai, X. Cai, W. Arfuso, Frank Sethi, G. Lobie, P. Goh, B. Lim, L. Hartman, M. Chan, C. Lee, S. Tan, S. Kumar, A. Triple negative breast cancer in Asia: An insider's view |
| title | Triple negative breast cancer in Asia: An insider's view |
| title_full | Triple negative breast cancer in Asia: An insider's view |
| title_fullStr | Triple negative breast cancer in Asia: An insider's view |
| title_full_unstemmed | Triple negative breast cancer in Asia: An insider's view |
| title_short | Triple negative breast cancer in Asia: An insider's view |
| title_sort | triple negative breast cancer in asia: an insider's view |
| url | http://hdl.handle.net/20.500.11937/61036 |