Osteogenic effects of a physical activity intervention in South African black children
Objectives: To determine whether a weight-bearing physical activity intervention improves measures of bone density, size and strength in a pre- and early pubertal cohort of black South African children. Methods: Twenty two school children (9.7±1.1 years) were cluster randomised into an exercise (EX;...
| Main Authors: | , , , |
|---|---|
| Format: | Journal Article |
| Published: |
2014
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pubmed/25198222 http://hdl.handle.net/20.500.11937/6088 |
| _version_ | 1848744975807807488 |
|---|---|
| author | Meiring, R. Micklesfield, L. Avidon, I. McVeigh, Joanne |
| author_facet | Meiring, R. Micklesfield, L. Avidon, I. McVeigh, Joanne |
| author_sort | Meiring, R. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objectives: To determine whether a weight-bearing physical activity intervention improves measures of bone density, size and strength in a pre- and early pubertal cohort of black South African children. Methods: Twenty two school children (9.7±1.1 years) were cluster randomised into an exercise (EX; n=12) and control (CON; n=10) group. EX children performed a weight-bearing exercise program for 20 weeks. CON children continued their regular activities. Whole body DXA and tibial peripheral QCT scans were obtained. Urine was analysed for concentrations of cross-linked N-telopeptides of Type I collagen (NTX).Results: Changes in 4% volumetric BMD, area and strength were greater in EX than CON. At the 38% site, change in bone area and density was greater in EX than CON. The greater change in periosteal circumference in the EX groups also resulted in a greater change in cortical thickness of the tibia compared to the CON group. NTX concentration was lower in the EX group than the CON group after the intervention. Conclusions: This study documents for the first time the beneficial response of trabecular and cortical bone of black children to a weight bearing exercise intervention. |
| first_indexed | 2025-11-14T06:10:00Z |
| format | Journal Article |
| id | curtin-20.500.11937-6088 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T06:10:00Z |
| publishDate | 2014 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-60882017-01-30T10:50:34Z Osteogenic effects of a physical activity intervention in South African black children Meiring, R. Micklesfield, L. Avidon, I. McVeigh, Joanne Objectives: To determine whether a weight-bearing physical activity intervention improves measures of bone density, size and strength in a pre- and early pubertal cohort of black South African children. Methods: Twenty two school children (9.7±1.1 years) were cluster randomised into an exercise (EX; n=12) and control (CON; n=10) group. EX children performed a weight-bearing exercise program for 20 weeks. CON children continued their regular activities. Whole body DXA and tibial peripheral QCT scans were obtained. Urine was analysed for concentrations of cross-linked N-telopeptides of Type I collagen (NTX).Results: Changes in 4% volumetric BMD, area and strength were greater in EX than CON. At the 38% site, change in bone area and density was greater in EX than CON. The greater change in periosteal circumference in the EX groups also resulted in a greater change in cortical thickness of the tibia compared to the CON group. NTX concentration was lower in the EX group than the CON group after the intervention. Conclusions: This study documents for the first time the beneficial response of trabecular and cortical bone of black children to a weight bearing exercise intervention. 2014 Journal Article http://hdl.handle.net/20.500.11937/6088 https://www.ncbi.nlm.nih.gov/pubmed/25198222 restricted |
| spellingShingle | Meiring, R. Micklesfield, L. Avidon, I. McVeigh, Joanne Osteogenic effects of a physical activity intervention in South African black children |
| title | Osteogenic effects of a physical activity intervention in South African black children |
| title_full | Osteogenic effects of a physical activity intervention in South African black children |
| title_fullStr | Osteogenic effects of a physical activity intervention in South African black children |
| title_full_unstemmed | Osteogenic effects of a physical activity intervention in South African black children |
| title_short | Osteogenic effects of a physical activity intervention in South African black children |
| title_sort | osteogenic effects of a physical activity intervention in south african black children |
| url | https://www.ncbi.nlm.nih.gov/pubmed/25198222 http://hdl.handle.net/20.500.11937/6088 |