MR imaging features of benign retroperitoneal paragangliomas and schwannomas
Background: To determine whether MRI feature analysis can differentiate benign retroperitoneal extra-adrenal paragangliomas and schwannomas. Methods: The MRI features of 50 patients with confirmed benign retroperitoneal extra-adrenal paragangliomas and schwannomas were retrospectively reviewed by tw...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
BioMed Central Ltd.
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/60621 |
| _version_ | 1848760620674973696 |
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| author | Shen, Y. Zhong, Y. Wang, H. Ma, L. Wang, Y. Zhang, K. Sun, Zhonghua Ye, H. |
| author_facet | Shen, Y. Zhong, Y. Wang, H. Ma, L. Wang, Y. Zhang, K. Sun, Zhonghua Ye, H. |
| author_sort | Shen, Y. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: To determine whether MRI feature analysis can differentiate benign retroperitoneal extra-adrenal paragangliomas and schwannomas. Methods: The MRI features of 50 patients with confirmed benign retroperitoneal extra-adrenal paragangliomas and schwannomas were retrospectively reviewed by two radiologists blinded to the histopathologic diagnosis. These features were compared between two types of tumours by use of the Mann-Whitney test and binary logistic regression. The patients’ clinical characteristics were reviewed. Results: Analysis of MRI images from 50 patients revealed no significant differences in the quantitative MRI features of lesion size, ratio of diameter and apparent diffusion coefficient. There were significant differences in the qualitative MRI features of location, necrosis, cysts and degree of tumour enhancement for two readers, with no significant differences in the other qualitative MRI features between these tumours. The combination of necrosis with degree of tumour enhancement during the arterial phase increased the probability that a retroperitoneal mass would represent retroperitoneal extra-adrenal paraganglioma as opposed to schwannoma. Conclusion: We have presented the largest series of MRI features of both benign retroperitoneal extra-adrenal paragangliomas and schwannomas. Some MRI features assist in the differentiation between these tumours, with imaging features consisting of necrosis and avid enhancement during the arterial phase, suggestive of retroperitoneal extra-adrenal paragangliomas |
| first_indexed | 2025-11-14T10:18:41Z |
| format | Journal Article |
| id | curtin-20.500.11937-60621 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:18:41Z |
| publishDate | 2018 |
| publisher | BioMed Central Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-606212025-04-28T02:59:18Z MR imaging features of benign retroperitoneal paragangliomas and schwannomas Shen, Y. Zhong, Y. Wang, H. Ma, L. Wang, Y. Zhang, K. Sun, Zhonghua Ye, H. Background: To determine whether MRI feature analysis can differentiate benign retroperitoneal extra-adrenal paragangliomas and schwannomas. Methods: The MRI features of 50 patients with confirmed benign retroperitoneal extra-adrenal paragangliomas and schwannomas were retrospectively reviewed by two radiologists blinded to the histopathologic diagnosis. These features were compared between two types of tumours by use of the Mann-Whitney test and binary logistic regression. The patients’ clinical characteristics were reviewed. Results: Analysis of MRI images from 50 patients revealed no significant differences in the quantitative MRI features of lesion size, ratio of diameter and apparent diffusion coefficient. There were significant differences in the qualitative MRI features of location, necrosis, cysts and degree of tumour enhancement for two readers, with no significant differences in the other qualitative MRI features between these tumours. The combination of necrosis with degree of tumour enhancement during the arterial phase increased the probability that a retroperitoneal mass would represent retroperitoneal extra-adrenal paraganglioma as opposed to schwannoma. Conclusion: We have presented the largest series of MRI features of both benign retroperitoneal extra-adrenal paragangliomas and schwannomas. Some MRI features assist in the differentiation between these tumours, with imaging features consisting of necrosis and avid enhancement during the arterial phase, suggestive of retroperitoneal extra-adrenal paragangliomas 2018 Journal Article http://hdl.handle.net/20.500.11937/60621 10.1186/s12883-017-0998-8 http://creativecommons.org/licenses/by/4.0/ BioMed Central Ltd. fulltext |
| spellingShingle | Shen, Y. Zhong, Y. Wang, H. Ma, L. Wang, Y. Zhang, K. Sun, Zhonghua Ye, H. MR imaging features of benign retroperitoneal paragangliomas and schwannomas |
| title | MR imaging features of benign retroperitoneal paragangliomas and schwannomas |
| title_full | MR imaging features of benign retroperitoneal paragangliomas and schwannomas |
| title_fullStr | MR imaging features of benign retroperitoneal paragangliomas and schwannomas |
| title_full_unstemmed | MR imaging features of benign retroperitoneal paragangliomas and schwannomas |
| title_short | MR imaging features of benign retroperitoneal paragangliomas and schwannomas |
| title_sort | mr imaging features of benign retroperitoneal paragangliomas and schwannomas |
| url | http://hdl.handle.net/20.500.11937/60621 |