Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts

Spring Onion (Allium fistolisum) is a promising source of bioactive moieties such as quercetin and flavonoids that exhibited various biological activities as anticancer and antioxidant. Samples of spring onion were analyzed using HPLC. Minerals profiling, antioxidant potential, and quantification...

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Main Authors: Aslam, Z., Akhtar, S., Imran, M., Nadeem, M., Gilani, S., Elnashar, Magdy, Ahmed, E.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/60596
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author Aslam, Z.
Akhtar, S.
Imran, M.
Nadeem, M.
Gilani, S.
Elnashar, Magdy
Ahmed, E.
author_facet Aslam, Z.
Akhtar, S.
Imran, M.
Nadeem, M.
Gilani, S.
Elnashar, Magdy
Ahmed, E.
author_sort Aslam, Z.
building Curtin Institutional Repository
collection Online Access
description Spring Onion (Allium fistolisum) is a promising source of bioactive moieties such as quercetin and flavonoids that exhibited various biological activities as anticancer and antioxidant. Samples of spring onion were analyzed using HPLC. Minerals profiling, antioxidant potential, and quantification of polyphenols were measured as indicators of antibacterial, anticancer, and anti-inflammatory activities. The quercetin and gallic acid contents in leaves and bulb portion were reported at 23.42±2.34 & 16.96±1.69 and 15.06±1.56 & 99.57±9.55, respectively. Likewise, chlorogenic and p-coumaric acid were quantified in leaves at 10.37±1.03, where as it was 12.33±1.23 in bulb portion. Results revealed that ethanol extract of the bulb portion exhibited the highest percentage inhibition of 10.45± 1.04% against anti-inflammatory activity as compared to methanol extract, 8.53 ± 0.85%.Similarly, bulb ethanolic and methanolic extracts of spring onion showed anticancer inhibition activities as 10.03 ± 1.00 & 31.00 ± 1.77%.In brief, spring onion has good anti-inflammatory, antimicrobial and anticancer potential and it is recommended to use these extracts on the pharmaceutical level.
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spelling curtin-20.500.11937-605962018-04-11T06:38:06Z Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts Aslam, Z. Akhtar, S. Imran, M. Nadeem, M. Gilani, S. Elnashar, Magdy Ahmed, E. Spring Onion (Allium fistolisum) is a promising source of bioactive moieties such as quercetin and flavonoids that exhibited various biological activities as anticancer and antioxidant. Samples of spring onion were analyzed using HPLC. Minerals profiling, antioxidant potential, and quantification of polyphenols were measured as indicators of antibacterial, anticancer, and anti-inflammatory activities. The quercetin and gallic acid contents in leaves and bulb portion were reported at 23.42±2.34 & 16.96±1.69 and 15.06±1.56 & 99.57±9.55, respectively. Likewise, chlorogenic and p-coumaric acid were quantified in leaves at 10.37±1.03, where as it was 12.33±1.23 in bulb portion. Results revealed that ethanol extract of the bulb portion exhibited the highest percentage inhibition of 10.45± 1.04% against anti-inflammatory activity as compared to methanol extract, 8.53 ± 0.85%.Similarly, bulb ethanolic and methanolic extracts of spring onion showed anticancer inhibition activities as 10.03 ± 1.00 & 31.00 ± 1.77%.In brief, spring onion has good anti-inflammatory, antimicrobial and anticancer potential and it is recommended to use these extracts on the pharmaceutical level. 2017 Journal Article http://hdl.handle.net/20.500.11937/60596 restricted
spellingShingle Aslam, Z.
Akhtar, S.
Imran, M.
Nadeem, M.
Gilani, S.
Elnashar, Magdy
Ahmed, E.
Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts
title Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts
title_full Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts
title_fullStr Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts
title_full_unstemmed Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts
title_short Antioxidant Activity, Anti-Inflammatory Activities, Anti-Cancer and Chemical Composition of Spring Onion (Allium Fistolisum) Extracts
title_sort antioxidant activity, anti-inflammatory activities, anti-cancer and chemical composition of spring onion (allium fistolisum) extracts
url http://hdl.handle.net/20.500.11937/60596