Alcohol intake and incidence of coronary disease in Australian Aborigines

Aims: To examine risk for coronary heart disease (CHD) and cardiovascular disease (CVD) in relation to alcohol in a cohort of Australian Aborigines. Methods: In 1988–1989, alcohol intake, drinking pattern, and beverage preference were elicited by interviewer-administered questionnaire in Western Aus...

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Main Authors: Burke, V., Lee, Andy, Hunter, E., Spargo, R., Smith, R., Beilin, L., Puddey, I.
Format: Journal Article
Published: Oxford University Press 2007
Online Access:http://hdl.handle.net/20.500.11937/5975
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author Burke, V.
Lee, Andy
Hunter, E.
Spargo, R.
Smith, R.
Beilin, L.
Puddey, I.
author_facet Burke, V.
Lee, Andy
Hunter, E.
Spargo, R.
Smith, R.
Beilin, L.
Puddey, I.
author_sort Burke, V.
building Curtin Institutional Repository
collection Online Access
description Aims: To examine risk for coronary heart disease (CHD) and cardiovascular disease (CVD) in relation to alcohol in a cohort of Australian Aborigines. Methods: In 1988–1989, alcohol intake, drinking pattern, and beverage preference were elicited by interviewer-administered questionnaire in Western Australian Aborigines (258 men, 256 women) and cardiovascular outcomes ascertained through linkage to mortality and hospital admission records to 2002. Results: In proportional hazards models, risk for CHD, relative to lifetime abstainers, was significantly increased in ex-drinkers [Hazard ratio (HR) 2.29, 95% CL 1.23, 4.27], those drinking 41–60 g/day in men or 21–40 g/day in women (HR 2.80, 95% CL 1.04, 7.53), and those drinking >150 g/day for men or >100 g/day for women (HR 2.25, 95% CL 1.03, 4.90) with a J-shaped relationship. Low-to-moderate drinkers had lower waist girth, exercised more, and had a lower prevalence of overweight and smoking than at-risk drinkers. A preference for wine was associated with lower HR (0.28, 95% CL 0.10, 0.95). With CVD, only ex-drinkers showed significantly increased risk (HR 1.87, 95% CL 1.20, 2.91). Conclusions: More favourable health-related behaviours in low-to-moderate drinkers suggest that lower risk could be mediated by lifestyle, as proposed in other populations.
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spelling curtin-20.500.11937-59752018-12-14T00:46:39Z Alcohol intake and incidence of coronary disease in Australian Aborigines Burke, V. Lee, Andy Hunter, E. Spargo, R. Smith, R. Beilin, L. Puddey, I. Aims: To examine risk for coronary heart disease (CHD) and cardiovascular disease (CVD) in relation to alcohol in a cohort of Australian Aborigines. Methods: In 1988–1989, alcohol intake, drinking pattern, and beverage preference were elicited by interviewer-administered questionnaire in Western Australian Aborigines (258 men, 256 women) and cardiovascular outcomes ascertained through linkage to mortality and hospital admission records to 2002. Results: In proportional hazards models, risk for CHD, relative to lifetime abstainers, was significantly increased in ex-drinkers [Hazard ratio (HR) 2.29, 95% CL 1.23, 4.27], those drinking 41–60 g/day in men or 21–40 g/day in women (HR 2.80, 95% CL 1.04, 7.53), and those drinking >150 g/day for men or >100 g/day for women (HR 2.25, 95% CL 1.03, 4.90) with a J-shaped relationship. Low-to-moderate drinkers had lower waist girth, exercised more, and had a lower prevalence of overweight and smoking than at-risk drinkers. A preference for wine was associated with lower HR (0.28, 95% CL 0.10, 0.95). With CVD, only ex-drinkers showed significantly increased risk (HR 1.87, 95% CL 1.20, 2.91). Conclusions: More favourable health-related behaviours in low-to-moderate drinkers suggest that lower risk could be mediated by lifestyle, as proposed in other populations. 2007 Journal Article http://hdl.handle.net/20.500.11937/5975 10.1093/alcalc/agl102 Oxford University Press unknown
spellingShingle Burke, V.
Lee, Andy
Hunter, E.
Spargo, R.
Smith, R.
Beilin, L.
Puddey, I.
Alcohol intake and incidence of coronary disease in Australian Aborigines
title Alcohol intake and incidence of coronary disease in Australian Aborigines
title_full Alcohol intake and incidence of coronary disease in Australian Aborigines
title_fullStr Alcohol intake and incidence of coronary disease in Australian Aborigines
title_full_unstemmed Alcohol intake and incidence of coronary disease in Australian Aborigines
title_short Alcohol intake and incidence of coronary disease in Australian Aborigines
title_sort alcohol intake and incidence of coronary disease in australian aborigines
url http://hdl.handle.net/20.500.11937/5975