The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia

Objective: This study examined the associations between 25-hydroxyvitamin D (25-OHD), dietary calcium (Ca) intake, and individual components of the metabolic syndrome (MetS). Methods: We analyzed a population-based sample of 18-75-year-old adults (n=3387) from the Victorian Health Monitor survey. Re...

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Main Authors: Pannu, P., Soares, Mario, Piers, L., Zhao, Y., Ansari, Z.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/59602
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author Pannu, P.
Soares, Mario
Piers, L.
Zhao, Y.
Ansari, Z.
author_facet Pannu, P.
Soares, Mario
Piers, L.
Zhao, Y.
Ansari, Z.
author_sort Pannu, P.
building Curtin Institutional Repository
collection Online Access
description Objective: This study examined the associations between 25-hydroxyvitamin D (25-OHD), dietary calcium (Ca) intake, and individual components of the metabolic syndrome (MetS). Methods: We analyzed a population-based sample of 18-75-year-old adults (n=3387) from the Victorian Health Monitor survey. Results: After adjustment for sociodemographic, physical, and dietary factors, as well as other MetS components, every 10 nmol/l increment in 25-OHD was associated with reduced adjusted odds ratio (AOR) of elevated triglycerides (TG) [AOR: 0.79, 95% confidence interval (CI): 0.74-0.84, P < 0.001], and higher fasting plasma glucose (AOR: 0.91, 95% CI: 0.86-0.96, P=0.002). After adjustment for confounders, every 500 mg/day increment in dietary Ca intake significantly reduced the odds of elevated diastolic blood pressure (AOR: 0.80, 95% CI: 0.66-0.99, P=0.038). When nine combinations of 25-OHD and Ca tertiles were examined, certain combinations were associated with reduced AOR for elevated TG (P < 0.001), when referenced against the combination of low 25-OHD (median: 33 nmol/l) and low Ca (median: 579 mg/day). At low 25-OHD, increasing Ca intake decreased the AOR for low high-density lipoprotein cholesterol in a dose-dependent manner, but at high 25-OHD; such effects of Ca were blunted. Conclusion: Higher vitamin D status and Ca intake or their combination were associated with reduced odds for a number of individual MetS components.
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spelling curtin-20.500.11937-596022018-03-29T03:49:01Z The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia Pannu, P. Soares, Mario Piers, L. Zhao, Y. Ansari, Z. Objective: This study examined the associations between 25-hydroxyvitamin D (25-OHD), dietary calcium (Ca) intake, and individual components of the metabolic syndrome (MetS). Methods: We analyzed a population-based sample of 18-75-year-old adults (n=3387) from the Victorian Health Monitor survey. Results: After adjustment for sociodemographic, physical, and dietary factors, as well as other MetS components, every 10 nmol/l increment in 25-OHD was associated with reduced adjusted odds ratio (AOR) of elevated triglycerides (TG) [AOR: 0.79, 95% confidence interval (CI): 0.74-0.84, P < 0.001], and higher fasting plasma glucose (AOR: 0.91, 95% CI: 0.86-0.96, P=0.002). After adjustment for confounders, every 500 mg/day increment in dietary Ca intake significantly reduced the odds of elevated diastolic blood pressure (AOR: 0.80, 95% CI: 0.66-0.99, P=0.038). When nine combinations of 25-OHD and Ca tertiles were examined, certain combinations were associated with reduced AOR for elevated TG (P < 0.001), when referenced against the combination of low 25-OHD (median: 33 nmol/l) and low Ca (median: 579 mg/day). At low 25-OHD, increasing Ca intake decreased the AOR for low high-density lipoprotein cholesterol in a dose-dependent manner, but at high 25-OHD; such effects of Ca were blunted. Conclusion: Higher vitamin D status and Ca intake or their combination were associated with reduced odds for a number of individual MetS components. 2017 Journal Article http://hdl.handle.net/20.500.11937/59602 10.1097/XCE.0000000000000133 restricted
spellingShingle Pannu, P.
Soares, Mario
Piers, L.
Zhao, Y.
Ansari, Z.
The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia
title The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia
title_full The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia
title_fullStr The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia
title_full_unstemmed The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia
title_short The association of Vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: A population-based study in Victoria, Australia
title_sort association of vitamin d status and dietary calcium intake with individual components of the metabolic syndrome: a population-based study in victoria, australia
url http://hdl.handle.net/20.500.11937/59602