Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture

How to add glycerol to maximize production of 1,3-propanediol (1,3-PD) is a critical problem in process control of microbial fermentation. Most of the existing works are focusing on modelling this process through deterministic-based differential equations. However, this process is not deterministic,...

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Main Authors: Wang, L., Yuan, J., Wu, Changzhi, Wang, X.
Format: Journal Article
Published: Springer Verlag 2017
Online Access:http://hdl.handle.net/20.500.11937/59573
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author Wang, L.
Yuan, J.
Wu, Changzhi
Wang, X.
author_facet Wang, L.
Yuan, J.
Wu, Changzhi
Wang, X.
author_sort Wang, L.
building Curtin Institutional Repository
collection Online Access
description How to add glycerol to maximize production of 1,3-propanediol (1,3-PD) is a critical problem in process control of microbial fermentation. Most of the existing works are focusing on modelling this process through deterministic-based differential equations. However, this process is not deterministic, but intrinsically stochastic considering nature of interference. Thus, it is of importance to consider stochastic microorganism. In this paper, we will modelling this process through stochastic differential equations and maximizing production of 1,3-PD is formulated as an optimal control problem subject to continuous state constraints and stochastic disturbances. A modified particle swarm algorithm through integrating the hybrid Monte Carlo sampling and path integral is proposed to solve this problem. The constraint transcription, local smoothing and time-scaling transformation are introduced to handle the continuous state constraints. Numerical results show that, by employing the obtained optimal control governed by stochastic dynamical system, 1,3-PD concentration at the terminal time can be increased compared with the previous results.
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format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:17:01Z
publishDate 2017
publisher Springer Verlag
recordtype eprints
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spelling curtin-20.500.11937-595732019-04-15T03:47:41Z Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture Wang, L. Yuan, J. Wu, Changzhi Wang, X. How to add glycerol to maximize production of 1,3-propanediol (1,3-PD) is a critical problem in process control of microbial fermentation. Most of the existing works are focusing on modelling this process through deterministic-based differential equations. However, this process is not deterministic, but intrinsically stochastic considering nature of interference. Thus, it is of importance to consider stochastic microorganism. In this paper, we will modelling this process through stochastic differential equations and maximizing production of 1,3-PD is formulated as an optimal control problem subject to continuous state constraints and stochastic disturbances. A modified particle swarm algorithm through integrating the hybrid Monte Carlo sampling and path integral is proposed to solve this problem. The constraint transcription, local smoothing and time-scaling transformation are introduced to handle the continuous state constraints. Numerical results show that, by employing the obtained optimal control governed by stochastic dynamical system, 1,3-PD concentration at the terminal time can be increased compared with the previous results. 2017 Journal Article http://hdl.handle.net/20.500.11937/59573 10.1007/s11590-017-1220-z Springer Verlag restricted
spellingShingle Wang, L.
Yuan, J.
Wu, Changzhi
Wang, X.
Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture
title Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture
title_full Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture
title_fullStr Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture
title_full_unstemmed Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture
title_short Practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture
title_sort practical algorithm for stochastic optimal control problem about microbial fermentation in batch culture
url http://hdl.handle.net/20.500.11937/59573