Specific combinations of ion channel inhibitors reduce excessive Ca2+ influx as a consequence of oxidative stress and increase neuronal and glial cell viability in vitro
Combinations of Ca 2+ channel inhibitors have been proposed as an effective means to prevent excess Ca 2+ flux and death of neurons and glia following neurotrauma in vivo. However, it is not yet known if beneficial outcomes such as improved viability have been due to direct effects on intracellular...
| Main Authors: | O'Hare Doig, R., Bartlett, C., Smith, N., Hodgetts, S., Dunlop, S., Hool, L., Fitzgerald, Melinda |
|---|---|
| Format: | Journal Article |
| Published: |
Pergamon
2016
|
| Online Access: | http://hdl.handle.net/20.500.11937/59506 |
Similar Items
Novel combinations of ion channel inhibitors for treatment of neurotrauma
by: O'Hare Doig, R., et al.
Published: (2015)
by: O'Hare Doig, R., et al.
Published: (2015)
Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma
by: Savigni, D., et al.
Published: (2013)
by: Savigni, D., et al.
Published: (2013)
Acute Cellular and Functional Changes With a Combinatorial Treatment of Ion Channel Inhibitors Following Spinal Cord Injury
by: O’Hare Doig, R.L., et al.
Published: (2020)
by: O’Hare Doig, R.L., et al.
Published: (2020)
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma
by: O'Hare Doig, R., et al.
Published: (2017)
by: O'Hare Doig, R., et al.
Published: (2017)
Reactive species and oxidative stress in optic nerve vulnerable to secondary degeneration
by: O'Hare Doig, R., et al.
Published: (2014)
by: O'Hare Doig, R., et al.
Published: (2014)
Delayed treatment of secondary degeneration following acute optic nerve transection using a combination of ion channel inhibitors
by: Yates, N., et al.
Published: (2017)
by: Yates, N., et al.
Published: (2017)
Changes in subtypes of Ca microdomains following partial injury to the central nervous system
by: Lozic, I., et al.
Published: (2014)
by: Lozic, I., et al.
Published: (2014)
PROTECTING GLIA FROM OXIDATIVE STRESS DURING SECONDARY DEGENERATION FOLLOWING NEUROTRAUMA
by: Doig, R., et al.
Published: (2014)
by: Doig, R., et al.
Published: (2014)
Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties
by: Meloni, B., et al.
Published: (2015)
by: Meloni, B., et al.
Published: (2015)
Poly(glycidyl methacrylate) Coated Dual Mode Upconverting Nanoparticles For Neuronal Cell Imaging
by: Smith, N., et al.
Published: (2016)
by: Smith, N., et al.
Published: (2016)
Repeated mild traumatic brain injury in female rats increases lipid peroxidation in neurons
by: Yates, N., et al.
Published: (2017)
by: Yates, N., et al.
Published: (2017)
AUX1-mediated root hair auxin influx governs SCFTIR1/AFB-type Ca2+ signaling
by: Dindas, Julian, et al.
Published: (2018)
by: Dindas, Julian, et al.
Published: (2018)
Thermal fluctuation and excess conductivity properties of YBCO-added CHITOSAN, CaO and Ca compound
by: Yap, Siew Hong
Published: (2024)
by: Yap, Siew Hong
Published: (2024)
Local varsities to see influx of Saudi students
Published: (2008)
Published: (2008)
Modelling cell cycle synchronisation in networks of coupled radial glial cells
by: Barrack, Duncan, et al.
Published: (2015)
by: Barrack, Duncan, et al.
Published: (2015)
SOX3 expression in the glial system of the developing and adult mouse cerebellum
by: Cheah, Pike‑See, et al.
Published: (2015)
by: Cheah, Pike‑See, et al.
Published: (2015)
Myelin Sheath Decompaction, Axon Swelling, and Functional Loss during Chronic Secondary Degeneration in Rat Optic Nerve
by: Payne, S., et al.
Published: (2012)
by: Payne, S., et al.
Published: (2012)
The effects of healthy ageing on glial cells in the rat spinal cord dorsal horn
by: Thompson, Aerin Edie
Published: (2022)
by: Thompson, Aerin Edie
Published: (2022)
Comparison of ion channel inhibitor combinations for limiting secondary degeneration following partial optic nerve transection
by: Toomey, L., et al.
Published: (2018)
by: Toomey, L., et al.
Published: (2018)
Plant embryogenesis requires AUX/LAX-mediated auxin influx
by: Robert, Hélène S, et al.
Published: (2015)
by: Robert, Hélène S, et al.
Published: (2015)
The managerial perspective on influx of foreign workers in construction companies in Pahang
by: Rosezaimee, Abdullah @ Ismail
Published: (2015)
by: Rosezaimee, Abdullah @ Ismail
Published: (2015)
Understanding The Influx Of Indonesian Immigrants In Rural Johor: Aspirations And Strategies
by: Ngah, Ibrahim, et al.
Published: (2016)
by: Ngah, Ibrahim, et al.
Published: (2016)
Early Proliferation Does Not Prevent the Loss of Oligodendrocyte Progenitor Cells during the Chronic Phase of Secondary Degeneration in a CNS White Matter Tract
by: Payne, S., et al.
Published: (2013)
by: Payne, S., et al.
Published: (2013)
Marine biota response to clastic sediment influx: A quantitative approach
by: Lokier, S., et al.
Published: (2009)
by: Lokier, S., et al.
Published: (2009)
The role of the tutor in supporting online engagement in higher education
by: O'Hare, Sheena
Published: (2014)
by: O'Hare, Sheena
Published: (2014)
Modern Yoga Practice and Human Rights as Reflexive, Embodied Experience
by: O'Hare, Kathleen
Published: (2017)
by: O'Hare, Kathleen
Published: (2017)
The role of gfi1b in zebrafish thrombopoiesis
by: O'Hare, Conor
Published: (2019)
by: O'Hare, Conor
Published: (2019)
A novel swarm-based optimisation algorithm inspired by artificial neural glial network for autonomous robots
by: Ismail, Amelia Ritahani, et al.
Published: (2019)
by: Ismail, Amelia Ritahani, et al.
Published: (2019)
Sequential induction of auxin efflux and influx carriers regulates lateral root emergence
by: Peret, Benjamin, et al.
Published: (2013)
by: Peret, Benjamin, et al.
Published: (2013)
The impacts of the influx of foreign workers on national economy / Nurul Syammimi Abdul Rahaman
by: Abdul Rahaman, Nurul Syammimi
Published: (2016)
by: Abdul Rahaman, Nurul Syammimi
Published: (2016)
Low temperature hydrothermal synthesis of calcium phosphate ceramics: effect of excess Ca precursor on phase behavior
by: Alqap, Asep Sofwan F., et al.
Published: (2009)
by: Alqap, Asep Sofwan F., et al.
Published: (2009)
Three dimensional electron microscopy reveals changing axonal and myelin morphology along normal and partially injured optic nerves
by: Giacci, M., et al.
Published: (2018)
by: Giacci, M., et al.
Published: (2018)
Vancomycin And Its Beta-Cyclodextrin Complex: Physicochemical Characterization And Its Cytotoxicity Evaluation On Human Glial Cell Line
by: SOFIAN, ZARIF MOHAMED
Published: (2011)
by: SOFIAN, ZARIF MOHAMED
Published: (2011)
Changes to mitochondrial ultrastructure in optic nerve vulnerable to secondary degeneration in vivo are limited by irradiation at 670 nm
by: Cummins, N., et al.
Published: (2013)
by: Cummins, N., et al.
Published: (2013)
Concurrent Glycogen and Lactate Imaging with FTIR Spectroscopy To Spatially Localize Metabolic Parameters of the Glial Response Following Brain Ischemia
by: Hackett, Mark, et al.
Published: (2016)
by: Hackett, Mark, et al.
Published: (2016)
Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root
by: Street, Ian H., et al.
Published: (2016)
by: Street, Ian H., et al.
Published: (2016)
The effects of a combination of ion channel inhibitors in female rats following repeated mild traumatic brain injury
by: Mao, Yilin, et al.
Published: (2018)
by: Mao, Yilin, et al.
Published: (2018)
Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection
by: Toomey, Lilian, et al.
Published: (2019)
by: Toomey, Lilian, et al.
Published: (2019)
The effects of concentration-dependent morphology of self-assembling RADA16 nanoscaffolds on mixed retinal cultures
by: Ho, D., et al.
Published: (2011)
by: Ho, D., et al.
Published: (2011)
Efficiency, Productivity, Excess
by: Bujalka, Eva
Published: (2022)
by: Bujalka, Eva
Published: (2022)
Similar Items
-
Novel combinations of ion channel inhibitors for treatment of neurotrauma
by: O'Hare Doig, R., et al.
Published: (2015) -
Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma
by: Savigni, D., et al.
Published: (2013) -
Acute Cellular and Functional Changes With a Combinatorial Treatment of Ion Channel Inhibitors Following Spinal Cord Injury
by: O’Hare Doig, R.L., et al.
Published: (2020) -
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma
by: O'Hare Doig, R., et al.
Published: (2017) -
Reactive species and oxidative stress in optic nerve vulnerable to secondary degeneration
by: O'Hare Doig, R., et al.
Published: (2014)