Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions
Human induced pluripotent stem (hiPS) cell lines CTRL-9-II and CTRL-10-I were derived from healthy monozygotic twin donors using non-integrating RNA based Sendai virus reprogramming and cultured in a xeno-free chemically defined condition. The established hiPS cell lines, CTRL-9-II and CTRL-10-I, ar...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Published: |
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/59462 |
| _version_ | 1848760487510016000 |
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| author | Uhlin, E. Rönnholm, H. Day, K. Kele, M. Tammimies, K. Bölte, Sven Falk, A. |
| author_facet | Uhlin, E. Rönnholm, H. Day, K. Kele, M. Tammimies, K. Bölte, Sven Falk, A. |
| author_sort | Uhlin, E. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Human induced pluripotent stem (hiPS) cell lines CTRL-9-II and CTRL-10-I were derived from healthy monozygotic twin donors using non-integrating RNA based Sendai virus reprogramming and cultured in a xeno-free chemically defined condition. The established hiPS cell lines, CTRL-9-II and CTRL-10-I, are karyotypically normal, free from reprogramming vectors, display endogenously expression of pluripotency factors at levels similar to embryonic stem cells. The generated iPS cell lines demonstrate pluripotency by passing bioinformatics assay PluriTest and by embryonic body assay. |
| first_indexed | 2025-11-14T10:16:34Z |
| format | Journal Article |
| id | curtin-20.500.11937-59462 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:16:34Z |
| publishDate | 2017 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-594622018-03-14T03:49:37Z Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions Uhlin, E. Rönnholm, H. Day, K. Kele, M. Tammimies, K. Bölte, Sven Falk, A. Human induced pluripotent stem (hiPS) cell lines CTRL-9-II and CTRL-10-I were derived from healthy monozygotic twin donors using non-integrating RNA based Sendai virus reprogramming and cultured in a xeno-free chemically defined condition. The established hiPS cell lines, CTRL-9-II and CTRL-10-I, are karyotypically normal, free from reprogramming vectors, display endogenously expression of pluripotency factors at levels similar to embryonic stem cells. The generated iPS cell lines demonstrate pluripotency by passing bioinformatics assay PluriTest and by embryonic body assay. 2017 Journal Article http://hdl.handle.net/20.500.11937/59462 10.1016/j.scr.2016.12.006 unknown |
| spellingShingle | Uhlin, E. Rönnholm, H. Day, K. Kele, M. Tammimies, K. Bölte, Sven Falk, A. Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions |
| title | Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions |
| title_full | Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions |
| title_fullStr | Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions |
| title_full_unstemmed | Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions |
| title_short | Derivation of human iPS cell lines from monozygotic twins in defined and xeno free conditions |
| title_sort | derivation of human ips cell lines from monozygotic twins in defined and xeno free conditions |
| url | http://hdl.handle.net/20.500.11937/59462 |