Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma

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Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma

Following neurotrauma, cells beyond the initial trauma site undergo secondary degeneration, with excess Ca 2+ a likely trigger for loss of neurons, compact myelin and function. Treatment using inhibitors of specific Ca 2+ channels has shown promise in preclinical studies, but clinical trials have...

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Bibliographic Details
Main Authors:	Savigni, D., O'Hare Doig, R., Szymanski, C., Bartlett, C., Lozic, I., Smith, N., Fitzgerald, Melinda
Format:	Journal Article
Published:	2013
Online Access:	http://hdl.handle.net/20.500.11937/59396

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