A multicomponent reaction of 2-aminoimidazoles: Microwave-assisted synthesis of novel 5-aza-7-deaza-adenines

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A multicomponent reaction of 2-aminoimidazoles: Microwave-assisted synthesis of novel 5-aza-7-deaza-adenines

An efficient and highly selective multicomponent synthesis of 4-aminoimidazo[1,2-a][1,3,5] triazines, which are 5-aza-7-deaza-isosteres of adenine, was developed. The reaction of 2-aminoimidazoles, triethyl orthoformate and cyanamide under microwave irradiation proceeded regioselectively to provide...

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Bibliographic Details
Main Authors:	Lim, F., Low, S., Ho, E., Halcovitch, N., Tiekink, E., Dolzhenko, Anton
Format:	Journal Article
Published:	Royal Society of Chemistry 2017
Online Access:	http://hdl.handle.net/20.500.11937/59385

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