Premature mortality in autism spectrum disorder
Background: Mortality has been suggested to be increased in autism spectrum disorder (ASD). Aims: To examine both all-cause and cause-specific mortality in ASD, as well as investigate moderating role of gender and intellectual ability. Method: Odds ratios (ORs) were calculated for a population-based...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
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Royal College of Psychiatrists
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/59202 |
| _version_ | 1848760413134520320 |
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| author | Hirvikoski, T. Mittendorfer-Rutz, E. Boman, M. Larsson, H. Lichtenstein, P. Bölte, Sven |
| author_facet | Hirvikoski, T. Mittendorfer-Rutz, E. Boman, M. Larsson, H. Lichtenstein, P. Bölte, Sven |
| author_sort | Hirvikoski, T. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Mortality has been suggested to be increased in autism spectrum disorder (ASD). Aims: To examine both all-cause and cause-specific mortality in ASD, as well as investigate moderating role of gender and intellectual ability. Method: Odds ratios (ORs) were calculated for a population-based cohort of ASD probands (n = 27 122, diagnosed between 1987 and 2009) compared with gender-, age-and county of residence-matched controls (n = 2 672 185). Results: During the observed period, 24 358 (0.91%) individuals in the general population died, whereas the corresponding figure for individuals with ASD was 706 (2.60%; OR = 2.56; 95% CI 2.38-2.76). Cause-specific analyses showed elevated mortality in ASD for almost all analysed diagnostic categories. Mortality and patterns for cause-specific mortality were partly moderated by gender and general intellectual ability. Conclusions: Premature mortality was markedly increased in ASD owing to a multitude of medical conditions. |
| first_indexed | 2025-11-14T10:15:23Z |
| format | Journal Article |
| id | curtin-20.500.11937-59202 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:15:23Z |
| publishDate | 2016 |
| publisher | Royal College of Psychiatrists |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-592022018-03-13T01:32:58Z Premature mortality in autism spectrum disorder Hirvikoski, T. Mittendorfer-Rutz, E. Boman, M. Larsson, H. Lichtenstein, P. Bölte, Sven Background: Mortality has been suggested to be increased in autism spectrum disorder (ASD). Aims: To examine both all-cause and cause-specific mortality in ASD, as well as investigate moderating role of gender and intellectual ability. Method: Odds ratios (ORs) were calculated for a population-based cohort of ASD probands (n = 27 122, diagnosed between 1987 and 2009) compared with gender-, age-and county of residence-matched controls (n = 2 672 185). Results: During the observed period, 24 358 (0.91%) individuals in the general population died, whereas the corresponding figure for individuals with ASD was 706 (2.60%; OR = 2.56; 95% CI 2.38-2.76). Cause-specific analyses showed elevated mortality in ASD for almost all analysed diagnostic categories. Mortality and patterns for cause-specific mortality were partly moderated by gender and general intellectual ability. Conclusions: Premature mortality was markedly increased in ASD owing to a multitude of medical conditions. 2016 Journal Article http://hdl.handle.net/20.500.11937/59202 10.1192/bjp.bp.114.160192 Royal College of Psychiatrists unknown |
| spellingShingle | Hirvikoski, T. Mittendorfer-Rutz, E. Boman, M. Larsson, H. Lichtenstein, P. Bölte, Sven Premature mortality in autism spectrum disorder |
| title | Premature mortality in autism spectrum disorder |
| title_full | Premature mortality in autism spectrum disorder |
| title_fullStr | Premature mortality in autism spectrum disorder |
| title_full_unstemmed | Premature mortality in autism spectrum disorder |
| title_short | Premature mortality in autism spectrum disorder |
| title_sort | premature mortality in autism spectrum disorder |
| url | http://hdl.handle.net/20.500.11937/59202 |