Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

QR Code

Suppression of adrenomedullin contributes to vascular leakage and altered epithelial repair during asthma

Background The anti-inflammatory peptide, adrenomedullin (AM), and its cognate receptor are expressed in lung tissue, but its pathophysiological significance in airway inflammation is unknown. Objectives This study investigated whether allergen-induced airway inflammation involves an impaired local...

Full description

Bibliographic Details
Main Authors:	Hagner, S., Welz, H., Kicic, Anthony, Alrifai, M., Marsh, L., Sutanto, E., Ling, K., Stick, S., Müller, B., Weissmann, N., Renz, H.
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/58828

Similar Items

Elucidating The Mechanisms Behind Defective Airway Epithelial Cell Repair In Childhood Asthma
by: Iosifidis, T., et al.
Published: (2015)

Reduced transforming growth factor ß1 (TGF-ß1) in the repair of airway epithelial cells of children with asthma
by: Ling, K., et al.
Published: (2016)

Intrinsic biochemical and functional differences in bronchial epithelial cells of children with asthma
by: Kicic, Anthony, et al.
Published: (2006)

DYSREGULATED NOTCH SIGNALING DURING ASTHMATIC AIRWAY EPITHELIAL REPAIR
by: Iosifidis, T., et al.
Published: (2018)

DETERMINING THE FUNDAMENTALS IN EPITHELIAL BARRIER INTEGRITY AND FUNCTION IN PAEDIATRIC ASTHMA
by: Looi, K., et al.
Published: (2016)

Dysregulated repair in asthmatic paediatric airway epithelial cells: The role of plasminogen activator inhibitor-1
by: Stevens, P.T., et al.
Published: (2008)

Effects of human rhinovirus on epithelial barrier integrity and function in children with asthma
by: Looi, K., et al.
Published: (2018)

Asthma and unified airways disease through epithelial cells
by: De Jong, E., et al.
Published: (2018)

ESTABLISHING MIGRATION TRAJECTORIES OF PRIMARY AIRWAY EPITHELIAL CELLS DURING WOUND REPAIR
by: Iosifidis, T., et al.
Published: (2015)

Airway epithelial repair in health and disease: Orchestrator or simply a player?
by: Iosifidis, T., et al.
Published: (2016)

Impaired airway epithelial cell responses from children with asthma to rhinoviral infection
by: Kicic, Anthony, et al.
Published: (2016)

Investigating the role of Adrenomedullin signalling during zebrafish development
by: Parker, Nathan
Published: (2025)

The Role Of Notch Signaling During Airway Epithelial Cell Repair After Injury
by: Iosifidis, T., et al.
Published: (2017)

Direct Evidence of Chronic Epithelial Injury and Dysregulated Repair in the Lung Allograft
by: Banerjee, B., et al.
Published: (2012)

ALPHA 1-ANTITRYPSIN MITIGATES NEUTROPHIL ELASTASE INHIBITION OF AIRWAY EPITHELIAL WOUND REPAIR IN CHILDREN WITH CYSTIC FIBROSIS
by: Garratt, L., et al.
Published: (2014)

Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase
by: Garratt, L.W., et al.
Published: (2016)

DYSREGULATED REPAIR AND EPITHELIAL INJURY IN SMALL AND LARGE AIRWAYS OF LUNG TRANSPLANT PATIENTS IS AMELIORATED BY AZITHROMYCIN
by: Kicic, Anthony, et al.
Published: (2014)

In vitro airway epithelial cell models differ in their functional response to neutrophil elastase exposure
by: Garratt, L., et al.
Published: (2013)

CULTURING SUCCESS OF CF AIRWAY EPITHELIAL CELLS (AEC) IS ASSOCIATED WITH DISEASE SPECIFIC FACTORS
by: Garratt, L., et al.
Published: (2013)

DEFECTIVE AIRWAY EPITHELIAL CELL REPAIR IN THE UPPER AND LOWER AIRWAYS OF ASTHMATICS: FURTHER EVIDENCE FOR THE UNIFIED AIRWAY HYPOTHESIS
by: Kicic, Anthony, et al.
Published: (2019)

Identification of Epithelial Phospholipase A2 Receptor 1 as a Potential Target in Asthma
by: Nolin, J., et al.
Published: (2016)

IDENTIFYING A NOVEL THERAPEUTIC STRATEGY FOR ASTHMA: TARGETING AIRWAY EPITHELIAL CELL RESTITUTION
by: Iosifidis, T., et al.
Published: (2017)

Transcription factor p63 regulates key genes and wound repair in human airway epithelial Basal cells
by: Warner, S., et al.
Published: (2013)

Epithelial Injury and Dysregulated Repair in Small and Large Airways of Lung Transplant Patients is Ameliorated by Azithromycin
by: Kicic, Anthony, et al.
Published: (2014)

Induction of epithelial-mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-β1
by: Hackett, T.L., et al.
Published: (2009)

Identification Of Epithelial Phospholipase A2 Receptor 1 (pla2r1) As A Target In Asthma
by: Hallstrand, T., et al.
Published: (2014)

Disruption of β-catenin/CBP signaling inhibits human airway epithelial-mesenchymal transition and repair
by: Moheimani, F., et al.
Published: (2015)

Comparison of techniques for obtaining lower airway epithelial cells from children
by: McNamara, P.S., et al.
Published: (2008)

The regenerative potential of epithelial stem cells in tissue repair
by: Arandjelovic, P., et al.
Published: (2014)

PROFILING INTEGRIN EXPRESSION ON ASTHMATIC AND NON-ASTHMATIC AIRWAY EPITHELIAL CELLS
by: Iosifidis, T., et al.
Published: (2014)

Corrective effects on airway epithelial function by human amniotic epithelial cells (HAEC) when treating cystic fibrosis
by: Kicic, Anthony, et al.
Published: (2015)

Dysregulated inflammatory and apoptotic responses to Human Rhinovirus in primary airway epithelial cells from young patients with cystic fibrosis
by: Stick, S.M., et al.
Published: (2010)

Evaluation of DNA repair biomarkers in epithelial ovarian and breast cancers
by: Shoqafi, Ahmed
Published: (2025)

Innate inflammatory responses of pediatric cystic fibrosis airway epithelial cells: Effects of nonviral and viral stimulation
by: Sutanto, E., et al.
Published: (2011)

FUNCTIONAL RESTORATION OF DF508 CFTR IN PRIMARY CYSTIC FIBROSIS AIRWAY EPITHELIAL CELLS
by: Sutanto, E., et al.
Published: (2009)

Efficient Restoration of dF508 CFTR Function in Primary Cystic Fibrosis Airway Epithelial Cells (AEC).
by: Stick, S.M., et al.
Published: (2009)

Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma
by: Bartel, S., et al.
Published: (2017)

TIGHT JUNCTION DISASSEMBLY FOLLOWING HUMAN RHINOVIRUS INFECTION RESULTS IN AIRWAY EPITHELIAL PERMEABILITY CHANGES
by: Looi, K., et al.
Published: (2014)

Alpha-1 antitrypsin ameliorates inhibition of wound repair by neutrophil elastase
by: Garratt, L., et al.
Published: (2014)

ASSESSING CF AIRWAY EPITHELIAL ANTIVIRAL RESPONSES FOLLOWING RHINOVIRAL INFECTION
by: Ling, K., et al.
Published: (2019)