Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes
Seasonal influenza can cause significant morbidity in pregnant women. Much of the existing epidemiological evidence on influenza during pregnancy has focused on the 2009 A/H1N1 pandemic. To measure the epidemiological characteristics of seasonal influenza infection among pregnant women and the impac...
| Main Authors: | , , , , |
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| Format: | Journal Article |
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Cambridge University Press
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/57894 |
| _version_ | 1848760125821550592 |
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| author | Regan, Annette Moore, H. Sullivan, S. DE Klerk, N. Effler, P. |
| author_facet | Regan, Annette Moore, H. Sullivan, S. DE Klerk, N. Effler, P. |
| author_sort | Regan, Annette |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Seasonal influenza can cause significant morbidity in pregnant women. Much of the existing epidemiological evidence on influenza during pregnancy has focused on the 2009 A/H1N1 pandemic. To measure the epidemiological characteristics of seasonal influenza infection among pregnant women and the impact on infant health, a cohort of 86 779 pregnancies during the influenza season (2012-2014) was established using probabilistic linkage of notifiable infectious disease, hospital admission, and birth information. A total of 192 laboratory-confirmed influenza infections were identified (2·2 per 1000 pregnancies), 14·6% of which were admitted to hospital. There was no difference in the proportion of infections admitted to hospital by trimester or subtype of infection. Influenza B infections were more likely to occur in second trimester compared with influenza A/H3N2 and influenza A/H1N1 infections (41·3%, 23·6%, and 33·3%, respectively), and on average, infants born to women with influenza B during pregnancy had 4·0% (95% CI 0·3-7·6%) lower birth weight relative to optimal compared with infants born to uninfected women (P = 0·03). Results from this linked population-based study suggest that there are differences in maternal infection by virus type and subtype and support the provision of seasonal influenza vaccine to pregnant women. |
| first_indexed | 2025-11-14T10:10:49Z |
| format | Journal Article |
| id | curtin-20.500.11937-57894 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:10:49Z |
| publishDate | 2017 |
| publisher | Cambridge University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-578942017-11-20T08:58:16Z Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes Regan, Annette Moore, H. Sullivan, S. DE Klerk, N. Effler, P. Seasonal influenza can cause significant morbidity in pregnant women. Much of the existing epidemiological evidence on influenza during pregnancy has focused on the 2009 A/H1N1 pandemic. To measure the epidemiological characteristics of seasonal influenza infection among pregnant women and the impact on infant health, a cohort of 86 779 pregnancies during the influenza season (2012-2014) was established using probabilistic linkage of notifiable infectious disease, hospital admission, and birth information. A total of 192 laboratory-confirmed influenza infections were identified (2·2 per 1000 pregnancies), 14·6% of which were admitted to hospital. There was no difference in the proportion of infections admitted to hospital by trimester or subtype of infection. Influenza B infections were more likely to occur in second trimester compared with influenza A/H3N2 and influenza A/H1N1 infections (41·3%, 23·6%, and 33·3%, respectively), and on average, infants born to women with influenza B during pregnancy had 4·0% (95% CI 0·3-7·6%) lower birth weight relative to optimal compared with infants born to uninfected women (P = 0·03). Results from this linked population-based study suggest that there are differences in maternal infection by virus type and subtype and support the provision of seasonal influenza vaccine to pregnant women. 2017 Journal Article http://hdl.handle.net/20.500.11937/57894 10.1017/S0950268817001972 Cambridge University Press restricted |
| spellingShingle | Regan, Annette Moore, H. Sullivan, S. DE Klerk, N. Effler, P. Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes |
| title | Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes |
| title_full | Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes |
| title_fullStr | Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes |
| title_full_unstemmed | Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes |
| title_short | Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes |
| title_sort | epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes |
| url | http://hdl.handle.net/20.500.11937/57894 |