Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction

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Long-term probucol therapy continues to suppress markers of neurovascular inflammation in a dietary induced model of cerebral capillary dysfunction

Background: Probucol has been shown to prevent cerebral capillary disturbances characterized by blood-to-brain extravasation of plasma derived proteins and neurovascular inflammation in mice maintained on western-styled diets for 12 weeks. However the effect of probucol on capillary integrity in agi...

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Bibliographic Details
Main Authors:	Takechi, Ryu, Pallebage-Gamarallage, Menuka, Lam, Virginie, Giles, Corey, Mamo, John
Format:	Journal Article
Published:	BioMed Central Ltd. 2014
Subjects:	Apolipoprotein B Probucol Brain capillaries Neuroinflammation Saturated fatty acids Amyloid-ß Blood–brain barrier Enterocytes
Online Access:	http://hdl.handle.net/20.500.11937/5769

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