Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES)
Aims: To evaluate the impact of community-based drug treatment on methamphetamine use using inverse probability of treatment-weighted (IPTW) estimators to derive treatment effects. Design: A longitudinal prospective cohort study with follow-ups at 3 months, 1 year and 3 years. Treatment effects were...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
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Wiley-Blackwell Publishing Ltd.
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/57050 |
| _version_ | 1848760002790031360 |
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| author | McKetin, Rebecca Najman, J. Baker, A. Lubman, D. Dawe, S. Ali, R. Lee, N. Mattick, R. Mamun, A. |
| author_facet | McKetin, Rebecca Najman, J. Baker, A. Lubman, D. Dawe, S. Ali, R. Lee, N. Mattick, R. Mamun, A. |
| author_sort | McKetin, Rebecca |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Aims: To evaluate the impact of community-based drug treatment on methamphetamine use using inverse probability of treatment-weighted (IPTW) estimators to derive treatment effects. Design: A longitudinal prospective cohort study with follow-ups at 3 months, 1 year and 3 years. Treatment effects were derived by comparing groups at follow-up. IPTW estimators were used to adjust for pre-treatment differences between groups. Setting: Sydney and Brisbane, Australia. Participants: Participants were methamphetamine users entering community-based detoxification (n=112) or residential rehabilitation (n=248) services and a quasi-control group of methamphetamine users (n=101) recruited from the community. Measurements: Frequency of methamphetamine use between interviews (no use, less than weekly, 1-2 days per week, 3+ days per week), continuous abstinence from methamphetamine use, past month methamphetamine use and methamphetamine dependence. Findings: Detoxification did not reduce methamphetamine use at any follow-up relative to the quasi-control group. Relative to quasi-control and detoxification groups combined, residential rehabilitation produced large reductions in the frequency of methamphetamine use at 3 months [odds ratio (OR)=0.23, 95% confidence interval (CI) 0.15-0.36, P < 0.001), with a marked attenuation of this effect at 1 year (OR 0.62, 95% CI 0.40-0.97, P=0.038) and 3 years (OR=0.71, 95% CI 0.42-1.19, P=0.189). The greatest impact was for abstinence: for every 100 residential rehabilitation clients there was a gain of 33 being continuously abstinent at 3 months, with this falling to 14 at 1 year and 6 at 3 years. Conclusions: Community-based residential rehabilitation may produce a time-limited decrease in methamphetamine use, while detoxification alone does not appear to do so. |
| first_indexed | 2025-11-14T10:08:51Z |
| format | Journal Article |
| id | curtin-20.500.11937-57050 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:08:51Z |
| publishDate | 2012 |
| publisher | Wiley-Blackwell Publishing Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-570502018-01-08T08:23:32Z Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES) McKetin, Rebecca Najman, J. Baker, A. Lubman, D. Dawe, S. Ali, R. Lee, N. Mattick, R. Mamun, A. Aims: To evaluate the impact of community-based drug treatment on methamphetamine use using inverse probability of treatment-weighted (IPTW) estimators to derive treatment effects. Design: A longitudinal prospective cohort study with follow-ups at 3 months, 1 year and 3 years. Treatment effects were derived by comparing groups at follow-up. IPTW estimators were used to adjust for pre-treatment differences between groups. Setting: Sydney and Brisbane, Australia. Participants: Participants were methamphetamine users entering community-based detoxification (n=112) or residential rehabilitation (n=248) services and a quasi-control group of methamphetamine users (n=101) recruited from the community. Measurements: Frequency of methamphetamine use between interviews (no use, less than weekly, 1-2 days per week, 3+ days per week), continuous abstinence from methamphetamine use, past month methamphetamine use and methamphetamine dependence. Findings: Detoxification did not reduce methamphetamine use at any follow-up relative to the quasi-control group. Relative to quasi-control and detoxification groups combined, residential rehabilitation produced large reductions in the frequency of methamphetamine use at 3 months [odds ratio (OR)=0.23, 95% confidence interval (CI) 0.15-0.36, P < 0.001), with a marked attenuation of this effect at 1 year (OR 0.62, 95% CI 0.40-0.97, P=0.038) and 3 years (OR=0.71, 95% CI 0.42-1.19, P=0.189). The greatest impact was for abstinence: for every 100 residential rehabilitation clients there was a gain of 33 being continuously abstinent at 3 months, with this falling to 14 at 1 year and 6 at 3 years. Conclusions: Community-based residential rehabilitation may produce a time-limited decrease in methamphetamine use, while detoxification alone does not appear to do so. 2012 Journal Article http://hdl.handle.net/20.500.11937/57050 10.1111/j.1360-0443.2012.03933.x Wiley-Blackwell Publishing Ltd. restricted |
| spellingShingle | McKetin, Rebecca Najman, J. Baker, A. Lubman, D. Dawe, S. Ali, R. Lee, N. Mattick, R. Mamun, A. Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES) |
| title | Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES) |
| title_full | Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES) |
| title_fullStr | Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES) |
| title_full_unstemmed | Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES) |
| title_short | Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES) |
| title_sort | evaluating the impact of community-based treatment options on methamphetamine use: findings from the methamphetamine treatment evaluation study (mates) |
| url | http://hdl.handle.net/20.500.11937/57050 |