Keratin 76 is required for tight junction function and maintenance of the skin barrier

QR Code

Keratin 76 is required for tight junction function and maintenance of the skin barrier

Keratins are cytoskeletal intermediate filament proteins that are increasingly being recognised for their diverse cellular functions. Here we report the consequences of germ line inactivation of Keratin 76 (Krt76) in mice. Homozygous disruption of this epidermally expressed gene causes neonatal skin...

Full description

Bibliographic Details
Main Authors:	DiTommaso, T., Cottle, D., Pearson, H., Schluter, H., Kaur, Pritinder, Humbert, P., Smyth, I.
Format:	Journal Article
Published:	Public Library of Science 2014
Online Access:	http://hdl.handle.net/20.500.11937/57029

Similar Items

The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis
by: Pearson, H., et al.
Published: (2015)

Myb via TGFβ is required for collagen type 1 production and skin integrity
by: Sampurno, S., et al.
Published: (2015)

Regulation of tight junction permeability by intestinal bacteria and dietary components
by: Ulluwishewa, Dulantha, et al.
Published: (2011)

Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells
by: Buckley, A., et al.
Published: (2018)

HUMAN RHINOVIRUS INFECTION INITIATES AIRWAY EPITHELIAL TIGHT JUNCTION DISASSEMBLY RESULTING IN BARRIER FUNCTION DISRUPTION
by: Looi, K., et al.
Published: (2013)

Intrinsic Differences Of Epithelial Tight Junctions In Asthmatic Airway Epithelium And Barrier Compromisation Following Human Rhinoviral Insult
by: Looi, K., et al.
Published: (2015)

Elucidation of clinical, environmental and T helper 2 factors on tight junction expressions in allergic rhinitis
by: Muhamad, Siti Nur Husna
Published: (2022)

Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment
by: Elahy, Mina, et al.
Published: (2015)

Investigating tight junction proteinrelated regulation of nasal epithelial barrier integrity in allergic rhinitis patients and non-allergic individuals
by: Othman, Siti Sarah Che
Published: (2023)

TIGHT JUNCTION DISASSEMBLY FOLLOWING HUMAN RHINOVIRUS INFECTION RESULTS IN AIRWAY EPITHELIAL PERMEABILITY CHANGES
by: Looi, K., et al.
Published: (2014)

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability
by: Looi, K., et al.
Published: (2016)

Keratin: an introduction
by: Sharma, Swati, et al.
Published: (2018)

Evaluation of Damage Mechanisms and Skin Factor in Tight Gas Reservoirs
by: Bahrami, Hassan, et al.
Published: (2011)

Evaluation of Damage Mechanisms and Skin Factor in Tight Gas Reservoirs
by: Bahrami, Hassan, et al.
Published: (2011)

Mesenchymal cells that support human skin regeneration
by: Gardner, J., et al.
Published: (2019)

Intrauterine Growth Restriction Mediates an Inflammatory Phenotype in Offspring but Does Not Affect Airway Epithelial Tight Junction Expression
by: Wang, K.C.W., et al.
Published: (2019)

HUMAN RHINOVIRUS INFECTION OF ASTHMATIC AIRWAY EPITHELIAL CELLS CAUSES TIGHT JUNCTION DISASSEMBLY RESULTING IN INCREASED PERMEABILITY
by: Looi, K., et al.
Published: (2013)

Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions
by: Gibson, Claire L., et al.
Published: (2014)

PERICYTES PROMOTE HUMAN SKIN TISSUE REGENERATION BY INCREASING SYMMETRIC DIVISIONS
by: Zhuang, L., et al.
Published: (2016)

Use of clotted human plasma and aprotinin in skin tissue engineering - A novel approach to engineering composite skin on a porous scaffold
by: Paul, M., et al.
Published: (2015)

Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
by: Assi, Reem Abou
Published: (2018)

Giardia duodenalis assemblage-specific induction of apoptosis and tight junction disruption in human intestinal epithelial cells: Effects of mixed infections
by: Koh, W., et al.
Published: (2012)

Efflux transporters and tight junction expression changes in human gastrointestinal cell lines cultured in defined medium vs serum supplemented medium
by: Warrier, A., et al.
Published: (2018)

Ionic liquids for keratin fibre modification
by: Trindade, Margarida
Published: (2022)

Formulation of Shampoo From Keratin Protein
by: Atikah, Mad Nawi
Published: (2013)

Less-tight versus tight control of hypertension in pregnancy
by: Magee, Laura A., et al.
Published: (2015)

Petronas untung RM76b
Published: (2008)

Petronas untung RM76b
Published: (2008)

Junction
by: Peel, Stuart
Published: (2008)

Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions.
by: Zhuang, L., et al.
Published: (2018)

Tight Gas
by: Aguilera, Roberto F, et al.
Published: (2012)

Production of beta-keratin from chicken feathers
by: Siti Aisyah Radhiah, Mohamed
Published: (2013)

Development of keratin based hydrogels for biomedical applications
by: Husain, M B S, et al.
Published: (2019)

Keratin-based bioplastic from chicken feathers
by: Gupta, Arun, et al.
Published: (2020)

Extraction of Keratin Protein from Chicken Feather
by: Gupta, Arun, et al.
Published: (2012)

Avian Keratin Fibre-Based Bio-Composites
by: Pourjavaheri, Firoozeh, et al.
Published: (2017)

DISASSEMBLY OF EPITHELIAL TIGHT JUNCTIONS IN WELL-DIFFERENTIATED AIR-LIQUID INTERFACE (ALI) CULTURES FOLLOWING HUMAN RHINOVIRUS INFECTION RESULTS IN AIRWAY EPITHELIAL PERMEABILITY CHANGES
by: Looi, K., et al.
Published: (2015)

Formulation of wound healing product from keratin protein
by: Nurdinie, Md Baliami
Published: (2013)

Formulation of Anti-Aging Cream from Keratin Protein
by: Nurhamizah, Ahmad Zaini
Published: (2013)

Formulation of Wound Healing Hydrogel from Keratin Protein
by: Rabiatul Adawiyah, Zaukifli
Published: (2012)

Cannot write session to /tmp/vufind_sessions/sess_r6ua9bp9jsdvjd430jvj4u957u