Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model
The population-based Basque Colorectal Cancer (CRC) Screening Programme started in 2009 with a biennial immunochemical quantitative test (FIT) biennial and colonoscopy under sedation in positive cases. The population target of 586,700 residents was from 50 to 69 years old and the total coverage was...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal Article |
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BioMed Central Ltd
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/56750 |
| _version_ | 1848759929415925760 |
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| author | Idigoras, I. Arrospide, A. Portillo, I. Arana-Arri, E. Martínez-Indart, L. Mar, J. De Koning, H. Lastra, R. Soto-Gordoa, M. van Der Meulen, M. Lansdorp-Vogelaar, Iris |
| author_facet | Idigoras, I. Arrospide, A. Portillo, I. Arana-Arri, E. Martínez-Indart, L. Mar, J. De Koning, H. Lastra, R. Soto-Gordoa, M. van Der Meulen, M. Lansdorp-Vogelaar, Iris |
| author_sort | Idigoras, I. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The population-based Basque Colorectal Cancer (CRC) Screening Programme started in 2009 with a biennial immunochemical quantitative test (FIT) biennial and colonoscopy under sedation in positive cases. The population target of 586,700 residents was from 50 to 69 years old and the total coverage was reached at the beginning of 2014. The aim of our study was to determine possible scenarios in terms of incidence, mortality and reduction of Life-years-Lost (L-y-L) in the medium and long term of CRC. Methods: Invitations were sent out by the Programme from 2009 to 2014, with combined organizational strategies. Simulation was done by MISCAN-colon (Microsimulation Screening Analysis) over 30 years comparing the results of screening vs no-screening, taking the population-based Cancer Registry into account. Lifetime population and real data from the Programme were used from 2008 to 2012. The model was run differentially for men and women. Results: 924,416 invitations were sent out from 2009 to 2014. The average participation rate was 68.4%, CRC detection rate was 3.4% and the Advanced Adenoma detection rate was 24.0‰, with differences observed in sex and age. Future scenarios showed a higher decrease of incidence (17.2% vs 14.7%), mortality (28.1% vs 22.4%) and L-y-L (22.6% vs 18.4%) in men than women in 2030. Conclusions: The Basque Country CRC Programme results are aligned to its strategy and comparable to other programmes. MISCAN model was found to be a useful tool to predict the benefits of the programme in the future. The effectiveness of the Programme has not been formally established as case control studies are required to determine long term benefits from the screening strategy. |
| first_indexed | 2025-11-14T10:07:41Z |
| format | Journal Article |
| id | curtin-20.500.11937-56750 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:07:41Z |
| publishDate | 2017 |
| publisher | BioMed Central Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-567502017-10-02T03:22:47Z Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model Idigoras, I. Arrospide, A. Portillo, I. Arana-Arri, E. Martínez-Indart, L. Mar, J. De Koning, H. Lastra, R. Soto-Gordoa, M. van Der Meulen, M. Lansdorp-Vogelaar, Iris The population-based Basque Colorectal Cancer (CRC) Screening Programme started in 2009 with a biennial immunochemical quantitative test (FIT) biennial and colonoscopy under sedation in positive cases. The population target of 586,700 residents was from 50 to 69 years old and the total coverage was reached at the beginning of 2014. The aim of our study was to determine possible scenarios in terms of incidence, mortality and reduction of Life-years-Lost (L-y-L) in the medium and long term of CRC. Methods: Invitations were sent out by the Programme from 2009 to 2014, with combined organizational strategies. Simulation was done by MISCAN-colon (Microsimulation Screening Analysis) over 30 years comparing the results of screening vs no-screening, taking the population-based Cancer Registry into account. Lifetime population and real data from the Programme were used from 2008 to 2012. The model was run differentially for men and women. Results: 924,416 invitations were sent out from 2009 to 2014. The average participation rate was 68.4%, CRC detection rate was 3.4% and the Advanced Adenoma detection rate was 24.0‰, with differences observed in sex and age. Future scenarios showed a higher decrease of incidence (17.2% vs 14.7%), mortality (28.1% vs 22.4%) and L-y-L (22.6% vs 18.4%) in men than women in 2030. Conclusions: The Basque Country CRC Programme results are aligned to its strategy and comparable to other programmes. MISCAN model was found to be a useful tool to predict the benefits of the programme in the future. The effectiveness of the Programme has not been formally established as case control studies are required to determine long term benefits from the screening strategy. 2017 Journal Article http://hdl.handle.net/20.500.11937/56750 10.1186/s12889-017-4639-3 http://creativecommons.org/licenses/by/4.0/ BioMed Central Ltd fulltext |
| spellingShingle | Idigoras, I. Arrospide, A. Portillo, I. Arana-Arri, E. Martínez-Indart, L. Mar, J. De Koning, H. Lastra, R. Soto-Gordoa, M. van Der Meulen, M. Lansdorp-Vogelaar, Iris Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model |
| title | Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model |
| title_full | Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model |
| title_fullStr | Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model |
| title_full_unstemmed | Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model |
| title_short | Evaluation of the colorectal cancer screening Programme in the Basque Country (Spain) and its effectiveness based on the Miscan-colon model |
| title_sort | evaluation of the colorectal cancer screening programme in the basque country (spain) and its effectiveness based on the miscan-colon model |
| url | http://hdl.handle.net/20.500.11937/56750 |