REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): Study protocol for a pilot randomised controlled trial

REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): Study protocol for a pilot randomised controlled trial

Background: Guidelines recommend an initial intravenous (IV) fluid bolus of 30 ml/kg isotonic crystalloid for patients with sepsis and hypotension. However, there is a lack of evidence from clinical trials to support this. Accumulating observational data suggest harm associated with the injudicious...

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Bibliographic Details
Main Authors: Macdonald, S., Taylor, D., Keijzers, G., Arendts, G., Fatovich, D., Kinnear, F., Brown, S., Bellomo, R., Burrows, S., Fraser, J., Litton, E., Ascencio-Lane, J., Anstey, Matthew, McCutcheon, D., Smart, L., Vlad, I., Winearls, J., Wibrow, B.
Format: Journal Article
Published: BioMed Central 2017
Online Access:http://hdl.handle.net/20.500.11937/56712

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