A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.

Quantitative analysis of the dynamics of tiny cellular and subcellular structures in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous similar targets in the presence of high levels of noise, high target density, man...

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Main Authors: Rezatofighi, S., Gould, S., Vo, Ba-Ngu, Mele, K., Hughes, W., Hartley, R.
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/56341
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author Rezatofighi, S.
Gould, S.
Vo, Ba-Ngu
Mele, K.
Hughes, W.
Hartley, R.
author_facet Rezatofighi, S.
Gould, S.
Vo, Ba-Ngu
Mele, K.
Hughes, W.
Hartley, R.
author_sort Rezatofighi, S.
building Curtin Institutional Repository
collection Online Access
description Quantitative analysis of the dynamics of tiny cellular and subcellular structures in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous similar targets in the presence of high levels of noise, high target density, maneuvering motion patterns and intricate interactions. The linear Gaussian jump Markov system probability hypothesis density (LGJMS-PHD) filter is a recent Bayesian tracking filter that is well-suited for this task. However, the existing recursion equations for this filter do not consider a state-dependent transition probability matrix. As required in many biological applications, we propose a new closed-form recursion that incorporates this assumption and introduce a general framework for particle tracking using the proposed filter. We apply our scheme to multi-target tracking in total internal reflection fluorescence microscopy (TIRFM) sequences and evaluate the performance of our filter against the existing LGJMS-PHD and IMM-JPDA filters.
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:06:26Z
publishDate 2013
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spelling curtin-20.500.11937-563412017-08-24T02:23:38Z A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences. Rezatofighi, S. Gould, S. Vo, Ba-Ngu Mele, K. Hughes, W. Hartley, R. Quantitative analysis of the dynamics of tiny cellular and subcellular structures in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous similar targets in the presence of high levels of noise, high target density, maneuvering motion patterns and intricate interactions. The linear Gaussian jump Markov system probability hypothesis density (LGJMS-PHD) filter is a recent Bayesian tracking filter that is well-suited for this task. However, the existing recursion equations for this filter do not consider a state-dependent transition probability matrix. As required in many biological applications, we propose a new closed-form recursion that incorporates this assumption and introduce a general framework for particle tracking using the proposed filter. We apply our scheme to multi-target tracking in total internal reflection fluorescence microscopy (TIRFM) sequences and evaluate the performance of our filter against the existing LGJMS-PHD and IMM-JPDA filters. 2013 Journal Article http://hdl.handle.net/20.500.11937/56341 restricted
spellingShingle Rezatofighi, S.
Gould, S.
Vo, Ba-Ngu
Mele, K.
Hughes, W.
Hartley, R.
A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.
title A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.
title_full A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.
title_fullStr A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.
title_full_unstemmed A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.
title_short A multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.
title_sort multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences.
url http://hdl.handle.net/20.500.11937/56341