Statins and skeletal muscles toxicity: From clinical trials to everyday practice

QR Code

Statins and skeletal muscles toxicity: From clinical trials to everyday practice

The mechanism(s) underlying the occurrence of statin-induced myopathy are ill defined, but the results of observational studies and clinical trials provide compelling evidence that skeletal muscle toxicity is a frequent, dose-dependent, adverse event associated with all statins. It has been suggeste...

Full description

Bibliographic Details
Main Authors:	Norata, Giuseppe, Tibolla, G., Catapano, A.
Format:	Journal Article
Published:	Academic Press 2014
Online Access:	http://hdl.handle.net/20.500.11937/56277

Similar Items

Therapy and clinical trials: Aggressive statin therapy versus combined and emerging approaches
by: Catapano, A., et al.
Published: (2011)

Statins and periodontal inflammation: A pleiotropic effect of statins or a pleiotropic effect of LDL-cholesterol lowering?
by: Norata, Giuseppe, et al.
Published: (2014)

Effect of Statins on Functional Expression of Membrane Transporters in L6 Rat Skeletal Muscle Cells
by: Bakar, Nur Salwani, et al.
Published: (2016)

Vascular inflammation and low-density lipoproteins: Is cholesterol the link? A lesson from the clinical trials
by: Catapano, A., et al.
Published: (2017)

PCSK9 inhibition in statin-intolerant HeFH patients: What's new?
by: Casula, M., et al.
Published: (2017)

Glutamine and skeletal muscle
by: Tirapegui, J., et al.
Published: (2015)

Regulation of skeletal muscle proteolysis
by: Slee, Adrian
Published: (2005)

Targeting PCSK9 for hypercholesterolemia
by: Norata, Giuseppe, et al.
Published: (2014)

PCSK9 inhibition for the treatment of hypercholesterolemia: Promises and emerging challenges
by: Norata, Giuseppe, et al.
Published: (2014)

Gene silencing approaches for the management of dyslipidaemia
by: Norata, Giuseppe, et al.
Published: (2013)

Endotoxin induced muscle wasting in avian and murine skeletal muscle
by: Tarabees, Reda Zakaria Ibrahim
Published: (2011)

GPCRs in rat primary skeletal muscle cells
by: Haddad, Mansour Emil Goerge
Published: (2012)

Hepatocellular carcinoma with disseminated skeletal muscle metastasis
by: Abdul Rahim, Ezamin, et al.
Published: (2017)

The heterogeneity of the functional, metabolic, and molecular responses of skeletal muscle and clinical adaptations to exercise training in pre-clinical and human models
by: Farrash, Wesam
Published: (2020)

HDL: To treat or not to treat?
by: Pirillo, A., et al.
Published: (2014)

Housekeeping proteins: How useful are they in skeletal muscle diabetes studies and muscle hypertrophy models?
by: Fortes, M., et al.
Published: (2016)

Long pentraxin 3: Experimental and clinical relevance in cardiovascular diseases
by: Bonacina, F., et al.
Published: (2013)

The role of skeletal muscle in the initiation and progression of knee osteoarthritis
by: Tonge, Daniel Paul
Published: (2010)

Calpain-10 and insulin resistance in human skeletal muscle
by: Norton, Luke
Published: (2007)

Molecular and metabolic regulation of skeletal muscle growth in chicken
by: Olomu, Charles
Published: (2018)

The effect of vitamin D on the development and function of skeletal muscle
by: Alliband, Kathryn
Published: (2024)

Bioactive scaffolds in skeletal muscle regeneration and tissue engineering
by: Chaturvedi, Vishal, et al.
Published: (2011)

PKCe as a novel promoter of skeletal muscle differentiation and regeneration
by: Di Marcantonio, D., et al.
Published: (2015)

Proprotein convertase subtilisin/kexin type 9 (PCSK9): From structure-function relation to therapeutic inhibition
by: Tibolla, G., et al.
Published: (2011)

Muscle size explains low passive skeletal muscle force in heart failure patients
by: Panizzolo, F., et al.
Published: (2016)

Mutations and polymorphisms of the skeletal muscle a-actin gene (ACTA1)
by: Laing, N., et al.
Published: (2009)

Molecular regulation of skeletal muscle myosin heavy chain isoforms
by: Brown, David M.
Published: (2015)

Skeletal muscle modulation and functional recovery after colonic resection
by: Bhalla, Ashish
Published: (2016)

The role of the vitamin D receptor in skeletal muscle protein metabolism
by: Bass, Joseph
Published: (2017)

The role of bioactive lipids and lipid binding proteins in skeletal muscle
by: Mohd Noor, Mohd Fadly
Published: (2019)

The impact of leucine-enriched whey protein on skeletal muscle anabolism
by: Ely, Isabel
Published: (2024)

Akt/protein kinase B in skeletal muscle physiology and pathology
by: Wu, M., et al.
Published: (2011)

Impact of polyphenols on lipid accumulation within skeletal muscle cells
by: Alhodieb, Fahad
Published: (2020)

Effects Of Oil Palm Plantation Tasks On Skeletal Muscle Activities
by: Nordin, Muhammad Nor Akmal
Published: (2022)

Nutraceuticals in the management of patients with statin-associated muscle symptoms, with a note on real-world experience
by: Ward, Natalie, et al.
Published: (2018)

Evaluation of skeletal muscle satellite cell activity in rodent models depicting muscle hypertrophy and atrophy
by: Sidique, Idris L.
Published: (2013)

PCSK9 inhibitors and dyslipidemia: The clinical evidence
by: Norata, Giuseppe
Published: (2014)

Counteracting age-related loss of skeletal muscle mass: a clinical and ethnological trial on the role of protein supplementation and training load (CALM Intervention Study): Study protocol for a randomized controlled trial- no UMP affiliation
by: Bechshøft, Rasmus Leidesdorff, et al.
Published: (2016)

Leonurine: A new comer in the natural compounds affecting atherosclerosis
by: Norata, Giuseppe, et al.
Published: (2012)

HDL and adaptive immunity: A tale of lipid rafts
by: Norata, Giuseppe, et al.
Published: (2012)

Cannot write session to /tmp/vufind_sessions/sess_v661eiocedu87is5o6om3rti7d