MicroRNA 143-145 deficiency impairs vascular function

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MicroRNA 143-145 deficiency impairs vascular function

MicroRNAs are required for vascular smooth muscle growth, differentiation and function. MiR143-145 modulates cytoskeletal dynamics and acquisition of the contractile phenotype by smooth muscle cells. Lack of this miRNA cluster results in decreased blood pressure and reduced vasocontraction. As all t...

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Bibliographic Details
Main Authors:	Norata, Giuseppe, Pinna, C., Zappella, F., Elia, L., Sala, A., Condorelli, G., Catapano, A.
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/56210

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