Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine a-hydroxylating monooxygenase (PHM)

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Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine a-hydroxylating monooxygenase (PHM)

Peptidyl a-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of a-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and as insecticides for the management of insect pest...

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Bibliographic Details
Main Authors:	Merkler, D., Asser, A., Baumgart, L., Carballo, N., Carpenter, S., Chew, G., Cosner, C., Dusi, J., Galloway, L., Lowe, Andrew, Lowe, E., King, L., Kendig, R., Kline, P., Malka, R., Merkler, K., McIntyre, N., Romero, M., Wilcox, B., Owen, T.
Format:	Journal Article
Published:	Pergamon 2008
Online Access:	http://hdl.handle.net/20.500.11937/5590

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