An Innovative Strategy for Dual Inhibitor Design and Its Application in Dual Inhibition of Human Thymidylate Synthase and Dihydrofolate Reductase Enzymes

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An Innovative Strategy for Dual Inhibitor Design and Its Application in Dual Inhibition of Human Thymidylate Synthase and Dihydrofolate Reductase Enzymes

Due to the diligence of inherent redundancy and robustness in many biological networks and pathways, multitarget inhibitors present a new prospect in the pharmaceutical industry for treatment of complex diseases. Nevertheless, to design multitarget inhibitors is concurrently a great challenge for me...

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Bibliographic Details
Main Authors:	Arooj, Mahreen, Sakkiah, Sugunadevi, Ping Cao, Guang, Woo Lee, Keun
Format:	Journal Article
Published:	Public Library of Science 2013
Online Access:	http://hdl.handle.net/20.500.11937/5567

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