Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline
© 2015 American Chemical Society. Cu(OTf) 2 and chiral BOX ligand-catalyzed 1,3-dipolar cycloadditions of triisopropylsilyl nitronates with a,ß-unsaturated carboximides produced chiral isoxazolines in high yields, high enantioselectivities, and complete diastereoselectivities. These chiral isoxazol...
| Main Authors: | , , |
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| Format: | Journal Article |
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American Chemical Society
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/55659 |
| _version_ | 1848759676479471616 |
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| author | Dong, Li Geng, C. Jiao, P. |
| author_facet | Dong, Li Geng, C. Jiao, P. |
| author_sort | Dong, Li |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2015 American Chemical Society. Cu(OTf) 2 and chiral BOX ligand-catalyzed 1,3-dipolar cycloadditions of triisopropylsilyl nitronates with a,ß-unsaturated carboximides produced chiral isoxazolines in high yields, high enantioselectivities, and complete diastereoselectivities. These chiral isoxazoline products were further converted into structurally diversified derivatives, which demonstrated the utility of the new method of constructing isoxazolines. The transition-state structure of cycloaddition was proposed in the light of the relative and absolute configurations of the products. |
| first_indexed | 2025-11-14T10:03:40Z |
| format | Journal Article |
| id | curtin-20.500.11937-55659 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:03:40Z |
| publishDate | 2015 |
| publisher | American Chemical Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-556592017-09-13T16:10:29Z Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline Dong, Li Geng, C. Jiao, P. © 2015 American Chemical Society. Cu(OTf) 2 and chiral BOX ligand-catalyzed 1,3-dipolar cycloadditions of triisopropylsilyl nitronates with a,ß-unsaturated carboximides produced chiral isoxazolines in high yields, high enantioselectivities, and complete diastereoselectivities. These chiral isoxazoline products were further converted into structurally diversified derivatives, which demonstrated the utility of the new method of constructing isoxazolines. The transition-state structure of cycloaddition was proposed in the light of the relative and absolute configurations of the products. 2015 Journal Article http://hdl.handle.net/20.500.11937/55659 10.1021/acs.joc.5b02035 American Chemical Society restricted |
| spellingShingle | Dong, Li Geng, C. Jiao, P. Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline |
| title | Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline |
| title_full | Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline |
| title_fullStr | Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline |
| title_full_unstemmed | Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline |
| title_short | Silyl Nitronate Cycloadditions Catalyzed by Cu(II)-Bisoxazoline |
| title_sort | silyl nitronate cycloadditions catalyzed by cu(ii)-bisoxazoline |
| url | http://hdl.handle.net/20.500.11937/55659 |