Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study

Several studies have examined associations between particulate matter with aerodynamic diameter of 2.5 m or less (PM 2.5 ) and preterm birth, but it is uncertain whether results were affected by individual predispositions (e.g., genetic factors, social conditions) that might vary considerably betwee...

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Main Authors: Pereira, Gavin, Belanger, K., Ebisu, K., Bell, M.
Format: Journal Article
Published: Oxford University Press 2014
Online Access:http://hdl.handle.net/20.500.11937/55471
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author Pereira, Gavin
Belanger, K.
Ebisu, K.
Bell, M.
author_facet Pereira, Gavin
Belanger, K.
Ebisu, K.
Bell, M.
author_sort Pereira, Gavin
building Curtin Institutional Repository
collection Online Access
description Several studies have examined associations between particulate matter with aerodynamic diameter of 2.5 m or less (PM 2.5 ) and preterm birth, but it is uncertain whether results were affected by individual predispositions (e.g., genetic factors, social conditions) that might vary considerably between women. We tested the hypothesis that a woman is at greater risk of preterm delivery when she has had elevated exposure to ambient PM 2.5 during a pregnancy than when she has not by comparing pregnancies in the same woman. From 271,204 births, we selected 29,175 women who had vaginal singleton livebirths at least twice in Connecticut in 2000-2006 (n = 61,688 births). Analyses matched pregnancies to the same woman. Adjusted odds ratios per interquartile range (2.33-g/m 3 ) increase in PM 2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.07 (95% confidence interval (CI): 1.00, 1.15), 0.96 (95% CI: 0.90, 1.03), 1.03 (95% CI: 0.97, 1.08), and 1.13 (95% CI: 1.01, 1.28), respectively. Among Hispanic women, the odds ratio per interquartile range increase in whole-pregnancy exposure was 1.31 (95% CI: 1.00, 1.73). Pregnancies with elevated PM 2.5 exposure were more likely to result in preterm birth than were other pregnancies to the same woman at lower exposure. Associations were most pronounced in the first trimester and among Hispanic women. © 2013 The Author.
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spelling curtin-20.500.11937-554712017-09-13T16:10:18Z Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study Pereira, Gavin Belanger, K. Ebisu, K. Bell, M. Several studies have examined associations between particulate matter with aerodynamic diameter of 2.5 m or less (PM 2.5 ) and preterm birth, but it is uncertain whether results were affected by individual predispositions (e.g., genetic factors, social conditions) that might vary considerably between women. We tested the hypothesis that a woman is at greater risk of preterm delivery when she has had elevated exposure to ambient PM 2.5 during a pregnancy than when she has not by comparing pregnancies in the same woman. From 271,204 births, we selected 29,175 women who had vaginal singleton livebirths at least twice in Connecticut in 2000-2006 (n = 61,688 births). Analyses matched pregnancies to the same woman. Adjusted odds ratios per interquartile range (2.33-g/m 3 ) increase in PM 2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.07 (95% confidence interval (CI): 1.00, 1.15), 0.96 (95% CI: 0.90, 1.03), 1.03 (95% CI: 0.97, 1.08), and 1.13 (95% CI: 1.01, 1.28), respectively. Among Hispanic women, the odds ratio per interquartile range increase in whole-pregnancy exposure was 1.31 (95% CI: 1.00, 1.73). Pregnancies with elevated PM 2.5 exposure were more likely to result in preterm birth than were other pregnancies to the same woman at lower exposure. Associations were most pronounced in the first trimester and among Hispanic women. © 2013 The Author. 2014 Journal Article http://hdl.handle.net/20.500.11937/55471 10.1093/aje/kwt216 Oxford University Press unknown
spellingShingle Pereira, Gavin
Belanger, K.
Ebisu, K.
Bell, M.
Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study
title Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study
title_full Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study
title_fullStr Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study
title_full_unstemmed Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study
title_short Fine particulate matter and risk of preterm birth in Connecticut in 2000-2006: A longitudinal study
title_sort fine particulate matter and risk of preterm birth in connecticut in 2000-2006: a longitudinal study
url http://hdl.handle.net/20.500.11937/55471