Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K

© 2017 American Chemical Society. The solubility of bicalutamide, megestrol acetate, prednisolone, beclomethasone dipropionate, and clarithromycin in subcritical water (SBCW) at the temperature range from 383.15 to 443.15 K and constant pressure of 5.5 MPa were measured using a modified solvent-anti...

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Main Authors: Pu, Y., Cai, F., Wang, D., Li, Y., Chen, X., Maimouna, A., Wu, Z., Wen, X., Chen, J., Foster, Neil
Format: Journal Article
Published: American Chemical Society 2017
Online Access:http://hdl.handle.net/20.500.11937/55256
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author Pu, Y.
Cai, F.
Wang, D.
Li, Y.
Chen, X.
Maimouna, A.
Wu, Z.
Wen, X.
Chen, J.
Foster, Neil
author_facet Pu, Y.
Cai, F.
Wang, D.
Li, Y.
Chen, X.
Maimouna, A.
Wu, Z.
Wen, X.
Chen, J.
Foster, Neil
author_sort Pu, Y.
building Curtin Institutional Repository
collection Online Access
description © 2017 American Chemical Society. The solubility of bicalutamide, megestrol acetate, prednisolone, beclomethasone dipropionate, and clarithromycin in subcritical water (SBCW) at the temperature range from 383.15 to 443.15 K and constant pressure of 5.5 MPa were measured using a modified solvent-antisolvent method combined with SBCW technology. The chemical structures of these five kinds of solutes were stable after processed in SBCW at up to 443.15 K, which was demonstrated by Fourier transformed infrared analysis. The solubility of selected solutes increased exponentially as the temperature of the SBCW increased from 383.15 to 443.15 K. The obtained solubility data were correlated using a modified Apelblat model and the results of the predicted solubility show good agreement with the experimental value. (Graph Presented).
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:02:03Z
publishDate 2017
publisher American Chemical Society
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spelling curtin-20.500.11937-552562017-09-13T16:10:38Z Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K Pu, Y. Cai, F. Wang, D. Li, Y. Chen, X. Maimouna, A. Wu, Z. Wen, X. Chen, J. Foster, Neil © 2017 American Chemical Society. The solubility of bicalutamide, megestrol acetate, prednisolone, beclomethasone dipropionate, and clarithromycin in subcritical water (SBCW) at the temperature range from 383.15 to 443.15 K and constant pressure of 5.5 MPa were measured using a modified solvent-antisolvent method combined with SBCW technology. The chemical structures of these five kinds of solutes were stable after processed in SBCW at up to 443.15 K, which was demonstrated by Fourier transformed infrared analysis. The solubility of selected solutes increased exponentially as the temperature of the SBCW increased from 383.15 to 443.15 K. The obtained solubility data were correlated using a modified Apelblat model and the results of the predicted solubility show good agreement with the experimental value. (Graph Presented). 2017 Journal Article http://hdl.handle.net/20.500.11937/55256 10.1021/acs.jced.6b00997 American Chemical Society restricted
spellingShingle Pu, Y.
Cai, F.
Wang, D.
Li, Y.
Chen, X.
Maimouna, A.
Wu, Z.
Wen, X.
Chen, J.
Foster, Neil
Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K
title Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K
title_full Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K
title_fullStr Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K
title_full_unstemmed Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K
title_short Solubility of Bicalutamide, Megestrol Acetate, Prednisolone, Beclomethasone Dipropionate, and Clarithromycin in Subcritical Water at Different Temperatures from 383.15 to 443.15 K
title_sort solubility of bicalutamide, megestrol acetate, prednisolone, beclomethasone dipropionate, and clarithromycin in subcritical water at different temperatures from 383.15 to 443.15 k
url http://hdl.handle.net/20.500.11937/55256