Stability and simulations of insonated contrast agents-effect of the constitutive law

Under insonation contrast agents are known to exhibit dynamic patterns such as thresholding, compression only behavior, diffusion and deflation, shape deformation, buckling, jetting and break-up, not all of which can be adequately predicted based on a single model describing the mechanics of the coa...

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Bibliographic Details
Main Authors: Pelekasis, N., Efthimiu, K., Tsigklifis, Konstantinos
Format: Conference Paper
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/55121
Description
Summary:Under insonation contrast agents are known to exhibit dynamic patterns such as thresholding, compression only behavior, diffusion and deflation, shape deformation, buckling, jetting and break-up, not all of which can be adequately predicted based on a single model describing the mechanics of the coating. Strain softening and strain hardening behavior in the presence of a folding instability are investigated as a means to understand compression only behavior in conjunction with the high harmonic content often recorded in optical and acoustic measurements of pulsating contrast agents coated by a phospholipid monolayer. Numerical simulations are presented that capture shape mode excitation and buckling of the coating and an association is made with the above phenomena.