Managing obstruction of the central airways

Lung cancer is the most common cause of cancer death in Australia, Europe and the USA. Up to 20-30% of these cancers eventually affect the central airways and result in reduced quality of life, dyspnoea, haemoptysis, post-obstructive pneumonia and ultimately death. Non-malignant processes may also l...

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Main Authors: Williamson, J., Phillips, M., Hillman, D., Eastwood, Peter
Format: Journal Article
Published: Blackwell Publishing 2010
Online Access:http://hdl.handle.net/20.500.11937/5506
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author Williamson, J.
Phillips, M.
Hillman, D.
Eastwood, Peter
author_facet Williamson, J.
Phillips, M.
Hillman, D.
Eastwood, Peter
author_sort Williamson, J.
building Curtin Institutional Repository
collection Online Access
description Lung cancer is the most common cause of cancer death in Australia, Europe and the USA. Up to 20-30% of these cancers eventually affect the central airways and result in reduced quality of life, dyspnoea, haemoptysis, post-obstructive pneumonia and ultimately death. Non-malignant processes may also lead to central airway obstruction and can have similar symptoms. With the development of newer technologies, the last 20 years have seen the emergence of the field of interventional pulmonology to deal specifically with the diagnosis and management of thoracic malignancy, including obstruction of the central airways. This review discusses the pathology, pre-procedure work-up and management options for obstructing central airway lesions. Several treatment modalities exist for dealing with endobronchial pathology with local availability and expertise guiding choice of treatment. While the literature lacks large, multicentre, randomized studies defining the optimal management strategy for a given problem, there is growing evidence from numerous case studies of improved physiology, of quality of life and possibly of survival with modern interventional techniques. © 2010 Royal Australasian College of Physicians.
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spelling curtin-20.500.11937-55062017-09-13T14:41:38Z Managing obstruction of the central airways Williamson, J. Phillips, M. Hillman, D. Eastwood, Peter Lung cancer is the most common cause of cancer death in Australia, Europe and the USA. Up to 20-30% of these cancers eventually affect the central airways and result in reduced quality of life, dyspnoea, haemoptysis, post-obstructive pneumonia and ultimately death. Non-malignant processes may also lead to central airway obstruction and can have similar symptoms. With the development of newer technologies, the last 20 years have seen the emergence of the field of interventional pulmonology to deal specifically with the diagnosis and management of thoracic malignancy, including obstruction of the central airways. This review discusses the pathology, pre-procedure work-up and management options for obstructing central airway lesions. Several treatment modalities exist for dealing with endobronchial pathology with local availability and expertise guiding choice of treatment. While the literature lacks large, multicentre, randomized studies defining the optimal management strategy for a given problem, there is growing evidence from numerous case studies of improved physiology, of quality of life and possibly of survival with modern interventional techniques. © 2010 Royal Australasian College of Physicians. 2010 Journal Article http://hdl.handle.net/20.500.11937/5506 10.1111/j.1445-5994.2009.02113.x Blackwell Publishing restricted
spellingShingle Williamson, J.
Phillips, M.
Hillman, D.
Eastwood, Peter
Managing obstruction of the central airways
title Managing obstruction of the central airways
title_full Managing obstruction of the central airways
title_fullStr Managing obstruction of the central airways
title_full_unstemmed Managing obstruction of the central airways
title_short Managing obstruction of the central airways
title_sort managing obstruction of the central airways
url http://hdl.handle.net/20.500.11937/5506