Synthesis and antiaggregant and hypotensive activity of benzo-annelated azabicyclo[m.n.0]alkanes

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Synthesis and antiaggregant and hypotensive activity of benzo-annelated azabicyclo[m.n.0]alkanes

Three-component condensation of veratrole, isobutylene oxide, and aliphatic omega-chloronitriles via the Ritter reaction leads to 1-(omega-chloroalkyl)-6,7-dimethoxy-3,3-dimethyl-3,4-dihydroisoquinolines, the reduction of which with NaBH4 yields benzoannelated azabicyclo[m.n.0]alkanes. The synthesiz...

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Bibliographic Details
Main Authors:	Glushkov, V., Stryapunina, O., Dolzhenko, Anton, Syropyatov, B., Shklyaev, Y.
Format:	Journal Article
Published:	Springer 2009
Online Access:	http://hdl.handle.net/20.500.11937/5503

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