Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor

Mechanisms by which blood cells sense shear stress are poorly characterized. In platelets, glycoprotein (GP)Ib-IX receptor complex has been long suggested to be a shear sensor and receptor. Recently, a relatively unstable and mechanosensitive domain in the GPIba subunit of GPIb-IX was identified. He...

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Bibliographic Details
Main Authors: Deng, W., Xu, Y., Chen, W., Paul, D., Syed, A., Dragovich, M., Liang, X., Zakas, P., Berndt, Michael, Di Paola, J., Ware, J., Lanza, F., Doering, C., Bergmeier, W., Zhang, X., Li, R.
Format: Journal Article
Published: Macmillan Publishers Limited 2016
Online Access:http://hdl.handle.net/20.500.11937/54969

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