Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data

Background: Low back pain (LBP) patients with related leg pain have a more severe profile than those with local LBP and a worse prognosis. Pain location above or below the knee and the presence of neurological signs differentiate patients with different profiles, but knowledge about the prognostic v...

Full description

Bibliographic Details
Main Authors: Kongsted, A., Kent, Peter, Jensen, T., Albert, H., Manniche, C.
Format: Journal Article
Published: Biomed Central Ltd 2013
Online Access:http://hdl.handle.net/20.500.11937/54854
_version_ 1848759479453089792
author Kongsted, A.
Kent, Peter
Jensen, T.
Albert, H.
Manniche, C.
author_facet Kongsted, A.
Kent, Peter
Jensen, T.
Albert, H.
Manniche, C.
author_sort Kongsted, A.
building Curtin Institutional Repository
collection Online Access
description Background: Low back pain (LBP) patients with related leg pain have a more severe profile than those with local LBP and a worse prognosis. Pain location above or below the knee and the presence of neurological signs differentiate patients with different profiles, but knowledge about the prognostic value of these subgroups is sparse. The objectives of this study were (1) to investigate whether subgroups consisting of patients with Local LBP only, LBP + leg pain above the knee, LBP + leg pain below the knee, and LBP + leg pain and neurological signs had different prognoses, and (2) to determine if this was explained by measured baseline factors. Methods. Routine clinical data were collected during the first visit to an outpatient department and follow-ups were performed after 3 and 12 months. Patients were divided into the four subgroups and associations between subgroups and the outcomes of activity limitation, global perceived effect (GPE) after 3 months, and sick leave after 3 months were tested by means of generalised estimating equations. Models were univariate (I), adjusted for duration (II), and adjusted for all baseline differences (III). Results: A total of 1,752 patients were included, with a 76% 3-month and 70% 12-month follow-up. Subgroups were associated with activity limitation in all models (p < 0.001). Local LBP had the least and LBP + neurological signs the most severe limitations at all time-points, although patients with neurological signs improved the most. Associations with GPE after 3 months were only significant in Model I. Subgroups were associated with sick leave after 3 months in model I and II, with sick leave being most frequent in the subgroup with neurological signs. No significant differences were found in any pairwise comparisons of patients with leg pain above or below the knee. Conclusions: Subgrouping LBP patients, based on pain location and neurological signs, was associated with activity limitation and sick leave, but not with GPE. The presence of neurological signs and pain in the leg both have prognostic implications but whether that leg pain without neurological signs is above or below the knee does not.
first_indexed 2025-11-14T10:00:32Z
format Journal Article
id curtin-20.500.11937-54854
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T10:00:32Z
publishDate 2013
publisher Biomed Central Ltd
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-548542017-09-13T16:09:32Z Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data Kongsted, A. Kent, Peter Jensen, T. Albert, H. Manniche, C. Background: Low back pain (LBP) patients with related leg pain have a more severe profile than those with local LBP and a worse prognosis. Pain location above or below the knee and the presence of neurological signs differentiate patients with different profiles, but knowledge about the prognostic value of these subgroups is sparse. The objectives of this study were (1) to investigate whether subgroups consisting of patients with Local LBP only, LBP + leg pain above the knee, LBP + leg pain below the knee, and LBP + leg pain and neurological signs had different prognoses, and (2) to determine if this was explained by measured baseline factors. Methods. Routine clinical data were collected during the first visit to an outpatient department and follow-ups were performed after 3 and 12 months. Patients were divided into the four subgroups and associations between subgroups and the outcomes of activity limitation, global perceived effect (GPE) after 3 months, and sick leave after 3 months were tested by means of generalised estimating equations. Models were univariate (I), adjusted for duration (II), and adjusted for all baseline differences (III). Results: A total of 1,752 patients were included, with a 76% 3-month and 70% 12-month follow-up. Subgroups were associated with activity limitation in all models (p < 0.001). Local LBP had the least and LBP + neurological signs the most severe limitations at all time-points, although patients with neurological signs improved the most. Associations with GPE after 3 months were only significant in Model I. Subgroups were associated with sick leave after 3 months in model I and II, with sick leave being most frequent in the subgroup with neurological signs. No significant differences were found in any pairwise comparisons of patients with leg pain above or below the knee. Conclusions: Subgrouping LBP patients, based on pain location and neurological signs, was associated with activity limitation and sick leave, but not with GPE. The presence of neurological signs and pain in the leg both have prognostic implications but whether that leg pain without neurological signs is above or below the knee does not. 2013 Journal Article http://hdl.handle.net/20.500.11937/54854 10.1186/1471-2474-14-171 http://creativecommons.org/licenses/by/2.0/ Biomed Central Ltd fulltext
spellingShingle Kongsted, A.
Kent, Peter
Jensen, T.
Albert, H.
Manniche, C.
Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data
title Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data
title_full Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data
title_fullStr Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data
title_full_unstemmed Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data
title_short Prognostic implications of the Quebec Task Force classification of back-related leg pain: An analysis of longitudinal routine clinical data
title_sort prognostic implications of the quebec task force classification of back-related leg pain: an analysis of longitudinal routine clinical data
url http://hdl.handle.net/20.500.11937/54854