Why and how back pain interventions work: What can we do to find out?

Mediation analysis is a useful research method that potentially allows identification of the mechanisms through which treatments affect patient outcomes. This chapter reviews the theoretical framework, research designs and statistical approaches used in mediation analysis. It describes what can be l...

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Main Authors: Mansell, G., Kamper, S., Kent, Peter
Format: Journal Article
Published: Bailliere Tindall 2013
Online Access:http://hdl.handle.net/20.500.11937/54774
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author Mansell, G.
Kamper, S.
Kent, Peter
author_facet Mansell, G.
Kamper, S.
Kent, Peter
author_sort Mansell, G.
building Curtin Institutional Repository
collection Online Access
description Mediation analysis is a useful research method that potentially allows identification of the mechanisms through which treatments affect patient outcomes. This chapter reviews the theoretical framework, research designs and statistical approaches used in mediation analysis. It describes what can be learnt from previous mediation research, much of which has investigated mediating factors of psychosocial interventions in other health conditions. It also summarises the few treatment-mediation studies of psychosocial interventions conducted in back pain. This chapter shows that there is emerging evidence about the role of some psychological factors as potential treatment mediators, such as self-efficacy and catastrophising. Mediation analysis can equally be applied to non-psychological factors. Pre-planned and appropriately conducted mediation analysis in adequately powered clinical trials would be a step forward in understanding treatment effects in back pain and improving patient management.
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institution Curtin University Malaysia
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spelling curtin-20.500.11937-547742017-09-13T16:11:35Z Why and how back pain interventions work: What can we do to find out? Mansell, G. Kamper, S. Kent, Peter Mediation analysis is a useful research method that potentially allows identification of the mechanisms through which treatments affect patient outcomes. This chapter reviews the theoretical framework, research designs and statistical approaches used in mediation analysis. It describes what can be learnt from previous mediation research, much of which has investigated mediating factors of psychosocial interventions in other health conditions. It also summarises the few treatment-mediation studies of psychosocial interventions conducted in back pain. This chapter shows that there is emerging evidence about the role of some psychological factors as potential treatment mediators, such as self-efficacy and catastrophising. Mediation analysis can equally be applied to non-psychological factors. Pre-planned and appropriately conducted mediation analysis in adequately powered clinical trials would be a step forward in understanding treatment effects in back pain and improving patient management. 2013 Journal Article http://hdl.handle.net/20.500.11937/54774 10.1016/j.berh.2013.10.001 http://creativecommons.org/licenses/by-nc-nd/4.0/ Bailliere Tindall fulltext
spellingShingle Mansell, G.
Kamper, S.
Kent, Peter
Why and how back pain interventions work: What can we do to find out?
title Why and how back pain interventions work: What can we do to find out?
title_full Why and how back pain interventions work: What can we do to find out?
title_fullStr Why and how back pain interventions work: What can we do to find out?
title_full_unstemmed Why and how back pain interventions work: What can we do to find out?
title_short Why and how back pain interventions work: What can we do to find out?
title_sort why and how back pain interventions work: what can we do to find out?
url http://hdl.handle.net/20.500.11937/54774