Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence
Background: Alcohol consumption, current injecting drug use, and pre-existing mental illness have been identified as 3 of the main reasons for excluding patients from treatment for hepatitis C. Objectives: We reviewed the literature to obtain an evidence base for these common exclusion criteria. Mat...
| Main Authors: | , , , |
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| Format: | Journal Article |
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Tehran Hepatitis Center
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/54407 |
| _version_ | 1848759363693445120 |
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| author | Higgs, Peter Sacks-Davis, R. Gold, J. Hellard, M. |
| author_facet | Higgs, Peter Sacks-Davis, R. Gold, J. Hellard, M. |
| author_sort | Higgs, Peter |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Alcohol consumption, current injecting drug use, and pre-existing mental illness have been identified as 3 of the main reasons for excluding patients from treatment for hepatitis C. Objectives: We reviewed the literature to obtain an evidence base for these common exclusion criteria. Materials and Methods: We reviewed original research and meta-analyses investigating the effects of alcohol consumption, current injecting drug use, and pre-existing mental illness. Results: We identified 66 study reports relevant to the review, but found only limited evidence to support withholding of treatment on the basis of the 3 previously mentioned exclusion criteria. Conclusions: Currently, there is a lack of evidence for many of the barriers faced by patients in availing treatment for hepatitis C. Adherence to treatment routine was found to be a better predictor of sustained virological response than injecting drug or alcohol consumption during treatment period or the presence of a pre-existing mental disorder. Although several challenges remain, we need to ensure that treatment decisions are based on the best available evidence and the treatment is performed appropriately on a case-by-case basis. © 2011 Kowsar M.P.Co. All rights reserved. |
| first_indexed | 2025-11-14T09:58:42Z |
| format | Journal Article |
| id | curtin-20.500.11937-54407 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:58:42Z |
| publishDate | 2011 |
| publisher | Tehran Hepatitis Center |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-544072017-07-27T05:20:57Z Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence Higgs, Peter Sacks-Davis, R. Gold, J. Hellard, M. Background: Alcohol consumption, current injecting drug use, and pre-existing mental illness have been identified as 3 of the main reasons for excluding patients from treatment for hepatitis C. Objectives: We reviewed the literature to obtain an evidence base for these common exclusion criteria. Materials and Methods: We reviewed original research and meta-analyses investigating the effects of alcohol consumption, current injecting drug use, and pre-existing mental illness. Results: We identified 66 study reports relevant to the review, but found only limited evidence to support withholding of treatment on the basis of the 3 previously mentioned exclusion criteria. Conclusions: Currently, there is a lack of evidence for many of the barriers faced by patients in availing treatment for hepatitis C. Adherence to treatment routine was found to be a better predictor of sustained virological response than injecting drug or alcohol consumption during treatment period or the presence of a pre-existing mental disorder. Although several challenges remain, we need to ensure that treatment decisions are based on the best available evidence and the treatment is performed appropriately on a case-by-case basis. © 2011 Kowsar M.P.Co. All rights reserved. 2011 Journal Article http://hdl.handle.net/20.500.11937/54407 Tehran Hepatitis Center restricted |
| spellingShingle | Higgs, Peter Sacks-Davis, R. Gold, J. Hellard, M. Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence |
| title | Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence |
| title_full | Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence |
| title_fullStr | Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence |
| title_full_unstemmed | Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence |
| title_short | Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence |
| title_sort | barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence |
| url | http://hdl.handle.net/20.500.11937/54407 |