Early detection of lung function abnormalities in young children with cystic fibrosis

The onset of lung disease in cystic fibrosis (CF) begins early in life with respiratory infection, inflammation, and structural lung damage all reported in infants with CF in the first months of life. As new treatments become available, it is essential that we have outcome measures that can be used...

Full description

Bibliographic Details
Main Authors: Gangell, C., Hall, Graham, Balding, E., Berry, L., Carlin, J., Carzino, R., de Klerk, N., Douglas, T., Ebdon, A., Foo, C., Garratt, L., Gibson, A., Harrison, J., Kicic, A., Laing, I., Logie, K., Massie, J., Mott, L., Murray, C., Poreddy, S., Ranganathan, S., Robertson, C., Robins-Browne, R., Robinson, P., Skoric, B.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/54273
_version_ 1848759330042544128
author Gangell, C.
Hall, Graham
Balding, E.
Berry, L.
Carlin, J.
Carzino, R.
de Klerk, N.
Douglas, T.
Ebdon, A.
Foo, C.
Gangell, C.
Garratt, L.
Gibson, A.
Harrison, J.
Kicic, A.
Laing, I.
Logie, K.
Massie, J.
Mott, L.
Murray, C.
Poreddy, S.
Ranganathan, S.
Robertson, C.
Robins-Browne, R.
Robinson, P.
Skoric, B.
author_facet Gangell, C.
Hall, Graham
Balding, E.
Berry, L.
Carlin, J.
Carzino, R.
de Klerk, N.
Douglas, T.
Ebdon, A.
Foo, C.
Gangell, C.
Garratt, L.
Gibson, A.
Harrison, J.
Kicic, A.
Laing, I.
Logie, K.
Massie, J.
Mott, L.
Murray, C.
Poreddy, S.
Ranganathan, S.
Robertson, C.
Robins-Browne, R.
Robinson, P.
Skoric, B.
author_sort Gangell, C.
building Curtin Institutional Repository
collection Online Access
description The onset of lung disease in cystic fibrosis (CF) begins early in life with respiratory infection, inflammation, and structural lung damage all reported in infants with CF in the first months of life. As new treatments become available, it is essential that we have outcome measures that can be used to track disease progression and treatment efficacy. In this review, we have examined the role of lung function testing in infants and preschool children with CF. In particular, we have focused on the ability of the various lung function tests to detect the presence of respiratory pathogens and structural lung disease, increased inflammation, and the onset of acute exacerbations.
first_indexed 2025-11-14T09:58:10Z
format Journal Article
id curtin-20.500.11937-54273
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T09:58:10Z
publishDate 2012
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-542732017-08-21T06:20:27Z Early detection of lung function abnormalities in young children with cystic fibrosis Gangell, C. Hall, Graham Balding, E. Berry, L. Carlin, J. Carzino, R. de Klerk, N. Douglas, T. Ebdon, A. Foo, C. Gangell, C. Garratt, L. Gibson, A. Harrison, J. Kicic, A. Laing, I. Logie, K. Massie, J. Mott, L. Murray, C. Poreddy, S. Ranganathan, S. Robertson, C. Robins-Browne, R. Robinson, P. Skoric, B. The onset of lung disease in cystic fibrosis (CF) begins early in life with respiratory infection, inflammation, and structural lung damage all reported in infants with CF in the first months of life. As new treatments become available, it is essential that we have outcome measures that can be used to track disease progression and treatment efficacy. In this review, we have examined the role of lung function testing in infants and preschool children with CF. In particular, we have focused on the ability of the various lung function tests to detect the presence of respiratory pathogens and structural lung disease, increased inflammation, and the onset of acute exacerbations. 2012 Journal Article http://hdl.handle.net/20.500.11937/54273 restricted
spellingShingle Gangell, C.
Hall, Graham
Balding, E.
Berry, L.
Carlin, J.
Carzino, R.
de Klerk, N.
Douglas, T.
Ebdon, A.
Foo, C.
Gangell, C.
Garratt, L.
Gibson, A.
Harrison, J.
Kicic, A.
Laing, I.
Logie, K.
Massie, J.
Mott, L.
Murray, C.
Poreddy, S.
Ranganathan, S.
Robertson, C.
Robins-Browne, R.
Robinson, P.
Skoric, B.
Early detection of lung function abnormalities in young children with cystic fibrosis
title Early detection of lung function abnormalities in young children with cystic fibrosis
title_full Early detection of lung function abnormalities in young children with cystic fibrosis
title_fullStr Early detection of lung function abnormalities in young children with cystic fibrosis
title_full_unstemmed Early detection of lung function abnormalities in young children with cystic fibrosis
title_short Early detection of lung function abnormalities in young children with cystic fibrosis
title_sort early detection of lung function abnormalities in young children with cystic fibrosis
url http://hdl.handle.net/20.500.11937/54273