The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain

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The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain

Secreted frizzled related proteins (SFRPs) are a family of Wnt regulators which are frequently downregulated in cancers. In malignant mesothelioma (MM), downregulation of SFRP4 has been reported as a mechanism which contributes to aberrant activation of oncogenic Wnt signaling. Here we investigated...

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Bibliographic Details
Main Authors:	Perumal, Vanathi, Dharmarajan, Arunasalam, Fox, Simon
Format:	Journal Article
Published:	Spandidos Publications 2017
Online Access:	http://hdl.handle.net/20.500.11937/54197

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